4-Chloro-6-hydrazinylpyrimidin-2-amine

Basic Information

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CAS Number

89124-04-9

Molecular Formula

C4H6ClN5

Molecular Weight

159.58 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

312.8±52.0 °C(Predicted)

Density

1.87±0.1 g/cm3(Predicted)

Flash Point

236.7°C

Refractive Index

1.766

SMILES

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C1=C(N=C(N=C1Cl)N)NN

InChI

InChI=1S/C4H6ClN5/c5-2-1-3(10-7)9-4(6)8-2/h1H,7H2,(H3,6,8,9,10)

InChIKey

PPECMSQKAVWRSP-UHFFFAOYSA-N

LogP

-0.002199999999999813

pKa

6.38±0.70(Predicted)

Topological Polar Surface Area

89.85 Å²

Hydrogen Bond Donor/Acceptor

5 / 5

Complexity

110

Synonyms & References

English

4-Chloro-6-hydrazinylpyrimidin-2-amine
(4-chloro-6-hydrazino-pyrimidin-2-yl)amine
4-chloro-6-hydrazino-2-pyrimidinamine
2-Pyrimidinamine, 4-chloro-6-hydrazinyl-
2-Pyrimidinamine,4-chloro-6-hydrazinyl-
4-Chloro-6-hydrazinopyrimidin-2-amine
4-chloro-6-hydrazinylpyrimidin-2-amine
AKOS000130395
SCHEMBL7171477
PPECMSQKAVWRSP-UHFFFAOYSA-N
CS-0225658
F87503
EN300-124571
89124-04-9
4-chloro-6-hydrazinopyrimidin-2-amine
DTXSID10283660
NSC32809
SB55953
LS-05247
2-pyrimidinamine, 4-chloro-6-hydrazino-
ALBB-016763
NSC-32809
MFCD09046417
2-amino-4-chloro-6-hydrazinopyrimidine

MDL Number

MFCD09046417

FAQ

What are the physical and chemical properties of 4-Chloro-6-hydrazinylpyrimidin-2-amine (CAS: 89124-04-9)?

4-Chloro-6-hydrazinylpyrimidin-2-amine is a white crystalline solid with a molecular weight of approximately 221.58 g/mol. It has a moderate solubility in water and is practically insoluble in organic solvents. The compound is moderately reactive, particularly with nucleophiles, and can form complexes with a variety of metal ions. It is stable under normal conditions but should be stored in a dry, shaded area to prevent hydrolysis.

How is 4-Chloro-6-hydrazinylpyrimidin-2-amine (CAS: 89124-04-9) typically synthesized?

4-Chloro-6-hydrazinylpyrimidin-2-amine is typically synthesized through a multi-step process involving the coupling of 4-chloropyrimidine with an hydrazine derivative. The reaction is usually performed in the presence of a catalyst such as triethylamine or N,N'-carbonyldiimidazole to improve the yield and selectivity. The overall process is known to provide good yields with high purity.

What industries use 4-Chloro-6-hydrazinylpyrimidin-2-amine (CAS: 89124-04-9)?

4-Chloro-6-hydrazinylpyrimidin-2-amine finds applications in the pharmaceutical industry, where it is used as an intermediate in the synthesis of various drugs. It is also utilized in the development of sensors and as a building block in the preparation of polymers and semiconductors. Its versatile nature makes it valuable in multiple sectors such as medicine, electronics, and materials science.

What precautions should be taken when handling 4-Chloro-6-hydrazinylpyrimidin-2-amine (CAS: 89124-04-9)?

When handling 4-Chloro-6-hydrazinylpyrimidin-2-amine, it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety glasses, and a lab coat. The compound should be used in a well-ventilated area or a fume hood to minimize exposure to fumes. Spills should be cleaned up using appropriate absorbents, and the area should be thoroughly washed down. In case of skin contact, wash the area with water and seek medical advice. Refer to the Safety Data Sheet (SDS) for more detailed information on handling and storage.