4-Chloro-6-hydrazinylpyrimidin-2-amine(CAS: 89124-04-9)

4-Chloro-6-hydrazinylpyrimidin-2-amine is a white crystalline solid with a molecular weight of approximately 221.58 g/mol. It has a moderate solubility in water and is practically insoluble in organic solvents. The compound is moderately reactive, particularly with nucleophiles, and can form complexes with a variety of metal ions. It is stable under normal conditions but should be stored in a dry, shaded area to prevent hydrolysis.

4-Chloro-6-hydrazinylpyrimidin-2-amine is typically synthesized through a multi-step process involving the coupling of 4-chloropyrimidine with an hydrazine derivative. The reaction is usually performed in the presence of a catalyst such as triethylamine or N,N'-carbonyldiimidazole to improve the yield and selectivity. The overall process is known to provide good yields with high purity.

4-Chloro-6-hydrazinylpyrimidin-2-amine finds applications in the pharmaceutical industry, where it is used as an intermediate in the synthesis of various drugs. It is also utilized in the development of sensors and as a building block in the preparation of polymers and semiconductors. Its versatile nature makes it valuable in multiple sectors such as medicine, electronics, and materials science.

When handling 4-Chloro-6-hydrazinylpyrimidin-2-amine, it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety glasses, and a lab coat. The compound should be used in a well-ventilated area or a fume hood to minimize exposure to fumes. Spills should be cleaned up using appropriate absorbents, and the area should be thoroughly washed down. In case of skin contact, wash the area with water and seek medical advice. Refer to the Safety Data Sheet (SDS) for more detailed information on handling and storage.