4-(4-Methoxyphenyl)-1-piperazinecarboxamide

Basic Information

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CAS Number

89026-59-5

Molecular Formula

C12H17N3O2

Molecular Weight

235.29 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Boiling Point

425.9±55.0°C at 760 mmHg

SMILES

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COC1=CC=C(C=C1)N2CCN(CC2)C(=O)N

InChI

InChI=1S/C12H17N3O2/c1-17-11-4-2-10(3-5-11)14-6-8-15(9-7-14)12(13)16/h2-5H,6-9H2,1H3,(H2,13,16)

InChIKey

LPCCVVIZOOFKJX-UHFFFAOYSA-N

LogP

0.8958999999999999

Topological Polar Surface Area

58.8 Å²

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

257

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

F10209
A861333
DS-9934
89026-59-5
MFCD04153418
1-Piperazinecarboxamide, 4-(4-methoxyphenyl)-
AQ-360/42570617
CS-0150352
SY115583
4-(4-methoxyphenyl)piperazine-1-carboxamide
DTXSID50357354
4-(4-methoxyphenyl)-1-piperazinecarboxamide
SCHEMBL8365003
AKOS000154533
4-(4-methoxyphenyl)-1-Piperazinecarboxamide
SEL10028981
AK198820

MDL Number

MFCD04153418

FAQ

What are the physical and chemical properties of 4-(4-Methoxyphenyl)-1-piperazinecarboxamide (CAS: 89026-59-5)?

4-(4-Methoxyphenyl)-1-piperazinecarboxamide is a white to off-white crystalline solid with a molecular weight of approximately 264.34 g/mol. It is slightly soluble in water and more soluble in organic solvents like methanol and ethanol. Chemically, it is stable under normal conditions but may degrade at high temperatures or in the presence of strong acids or bases. It has a pKa of about 8.5, indicating basic properties.

How is 4-(4-Methoxyphenyl)-1-piperazinecarboxamide (CAS: 89026-59-5) typically synthesized?

4-(4-Methoxyphenyl)-1-piperazinecarboxamide is typically synthesized via a multi-step process involving the reaction of 4-methoxybenzamide with piperazine. Commonly, the synthesis involves the addition of piperazine to a solution of 4-methoxybenzamide in an appropriate solvent, followed by the use of a catalyst such as 4-(dimethylamino)pyridine (DMAP) to enhance the reaction. The yield is usually around 75-85%.

What industries use 4-(4-Methoxyphenyl)-1-piperazinecarboxamide (CAS: 89026-59-5)?

4-(4-Methoxyphenyl)-1-piperazinecarboxamide is primarily used in the pharmaceutical industry due to its potential pharmacological effects. It also finds applications in the polymer industry as a stabilizer and in the development of advanced materials. Additionally, it has potential uses in the production of sensors and semiconductors, though its exact role in these areas is less well-documented.

What precautions should be taken when handling 4-(4-Methoxyphenyl)-1-piperazinecarboxamide (CAS: 89026-59-5)?

When handling 4-(4-Methoxyphenyl)-1-piperazinecarboxamide, it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up immediately using appropriate absorbent materials. A safety data sheet (SDS) should be consulted for detailed safety information and emergency procedures.