5,6-Dichloropicolinic acid

Basic Information

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CAS Number

88912-24-7

Molecular Formula

C6H3Cl2NO2

Molecular Weight

192 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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C1=CC(=NC(=C1Cl)Cl)C(=O)O

InChI

InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(6(10)11)9-5(3)8/h1-2H,(H,10,11)

InChIKey

QOJNAEPFSUYAFL-UHFFFAOYSA-N

LogP

2.0866

Topological Polar Surface Area

50.19 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

165

Synonyms & References

English

5,6-Dichloropicolinic acid
2-Pyridinecarboxylic acid, 5,6-dichloro-
5,6-dichloro-2-Pyridinecarboxylic acid
5,6-Dichloropyridine-2-carboxylic acid
C6H3Cl2NO2
2,3-DICHLORO-6-CARBOXYPYRIDINE
2-Pyridinecarboxylicacid, 5,6-dichloro-
QOJNAEPFSUYAFL-UHFFFAOYSA-N
2,3-dichloro-6-pyridinecarboxylicacid
AS04712
AM62362
2,3-Dichloro-6-pyridinecarboxylic acid
5
5,6-Dichloro-2-pyridinecarboxylic acid (ACI)
SCHEMBL3632915
88912-24-7
SY112665
5 pound not6-Dichloropicolinic acid
5,6-Dichloro-2-pyridinecarboxylic acid
DB-358681
5,6-dichloropyridine-2-carboxylic acid
MFCD13185546
5,6-Dichloro-pyridine-2-carboxylic acid
AKOS015999456
DTXSID30534141
CS-W009205
GS-3701

MDL Number

MFCD13185546

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 5,6-Dichloropicolinic acid (CAS: 88912-24-7)?

5,6-Dichloropicolinic acid (CAS: 88912-24-7) is a white crystalline solid with a molecular weight of approximately 225.03 g/mol. It is sparingly soluble in water and has limited solubility in organic solvents. This compound is known for its acidic nature, with a pKa of around 1.4. It is also relatively stable, but can react with bases to form salts.

How is 5,6-Dichloropicolinic acid (CAS: 88912-24-7) typically synthesized?

5,6-Dichloropicolinic acid can be synthesized via the chlorination of picolinic acid under appropriate conditions. A common method involves treating picolinic acid with chlorine gas in the presence of a suitable catalyst, such as ferric chloride, to selectively introduce the dichloro substituents. The yield and selectivity of the reaction can be significantly influenced by the reaction conditions and the choice of catalyst.

What industries use 5,6-Dichloropicolinic acid (CAS: 88912-24-7)?

5,6-Dichloropicolinic acid is used in various industries. It is a key intermediate in the synthesis of pharmaceuticals, particularly in the development of antibacterial and anticancer drugs. It also finds applications in the production of polymers and as a component in sensors and semiconductors.

What precautions should be taken when handling 5,6-Dichloropicolinic acid (CAS: 88912-24-7)?

When handling 5,6-Dichloropicolinic acid (CAS: 88912-24-7), it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The substance should be stored in a well-ventilated area, and work should be conducted in a fume hood to minimize exposure. Spills should be handled with caution, using appropriate cleanup materials. Refer to the safety data sheet (SDS) for detailed emergency procedures and storage guidelines.