1-(2,6-Difluoro-4-methoxyphenyl)ethanone

Basic Information

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CAS Number

886498-84-6

Molecular Formula

C9H8F2O2

Molecular Weight

186.16 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

SMILES

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CC(=O)C1=C(C=C(C=C1F)OC)F

InChI

InChI=1S/C9H8F2O2/c1-5(12)9-7(10)3-6(13-2)4-8(9)11/h3-4H,1-2H3

InChIKey

YZVNPIUPAKOREH-UHFFFAOYSA-N

LogP

2.176

Topological Polar Surface Area

26.3 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

184

Synonyms & References

English

SCHEMBL2382494
MFCD04115921
886498-84-6
YZVNPIUPAKOREH-UHFFFAOYSA-N
AC-26274
MS-20106
EN300-201670
A842810
CL9315
2',6'-Difluoro-4'-methoxyacetophenone
1-(2,6-difluoro-4-methoxyphenyl)ethanone
2 ,6 -Difluoro-4 -methoxyacetophenone
AKOS005256481
AMY202100131
1-(2,6-difluoro-4-methoxyphenyl)ethan-1-one
DTXSID40397345
1-(2,6-difluoro-4-methoxy-phenyl)ethanone
1-(2,6-Difluoro-4-methoxyphenyl)ethanone
JRD-1437

MDL Number

MFCD04115921

FAQ

What are the physical and chemical properties of 1-(2,6-Difluoro-4-methoxyphenyl)ethanone (CAS: 886498-84-6)?

1-(2,6-Difluoro-4-methoxyphenyl)ethanone is a white crystalline solid with a molecular weight of approximately 224.15 g/mol. It is slightly soluble in water and has good solubility in organic solvents like ethanol and acetone. The compound exhibits good stability under normal conditions but can react with strong nucleophiles. It is also known for its high reactivity towards reduction and oxidation processes.

How is 1-(2,6-Difluoro-4-methoxyphenyl)ethanone (CAS: 886498-84-6) typically synthesized?

1-(2,6-Difluoro-4-methoxyphenyl)ethanone can be synthesized via a two-step process involving the protection of an alcohol followed by an electrophilic aromatic substitution. Common solvents for the reactions are dichloromethane or tetrahydrofuran. The use of a Lewis acid catalyst, such as aluminum chloride, is typical for the electrophilic substitution step. The overall yield is generally around 70-80%.

What industries use 1-(2,6-Difluoro-4-methoxyphenyl)ethanone (CAS: 886498-84-6)?

1-(2,6-Difluoro-4-methoxyphenyl)ethanone is primarily used in the pharmaceutical industry for the synthesis of various intermediates and active pharmaceutical ingredients. It also finds applications in the polymer industry for the development of specialized polymers and in the sensor industry for the production of gas sensors. Additionally, it may be used in semiconductor manufacturing for certain etching processes.

What precautions should be taken when handling 1-(2,6-Difluoro-4-methoxyphenyl)ethanone (CAS: 886498-84-6)?

When handling 1-(2,6-Difluoro-4-methoxyphenyl)ethanone, it is crucial to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. Work should be performed in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate absorbents and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and emergency procedures.