6-Bromo[1,3]oxazolo[5,4-b]pyridine

Basic Information

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CAS Number

886372-90-3

Molecular Formula

C6H3BrN2O

Molecular Weight

199.01 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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C1=C(C=NC2=C1N=CO2)Br

InChI

InChI=1S/C6H3BrN2O/c7-4-1-5-6(8-2-4)10-3-9-5/h1-3H

InChIKey

ZFNFJJDYESCFHJ-UHFFFAOYSA-N

LogP

1.9852999999999998

Topological Polar Surface Area

38.92 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

133

Synonyms & References

English

AKOS006284603
EN300-136240
6-Bromooxazolo[5,4-b]pyridine
6-Bromo[1,3]oxazolo[5,4-b]pyridine
6-bromo-[1,3]oxazolo[5,4-b]pyridine
886372-90-3
MFCD07375014
AM20061592
AC-29936
FT-0753052
DTXSID70716944
SY036738
F8889-0238
FS-3159
6-Bromo-oxazolo[5,4-b]pyridine
AB40951
6-BROMO-OXAZOLO[5,4-B]PYRIDINE
6-Bromooxazolo[5,4-b]pyridine (ACI)

MDL Number

MFCD07375014

FAQ

What are the physical and chemical properties of 6-Bromo[1,3]oxazolo[5,4-b]pyridine (CAS: 886372-90-3)?

6-Bromo[1,3]oxazolo[5,4-b]pyridine is a crystalline solid with a molecular weight of approximately 254.04 g/mol. It has a low solubility in water but is more soluble in organic solvents like dichloromethane and ethanol. Chemically, it is moderately reactive, particularly towards nucleophiles, and can undergo substitution reactions. It has a melting point around 150-155°C.

How is 6-Bromo[1,3]oxazolo[5,4-b]pyridine (CAS: 886372-90-3) typically synthesized?

6-Bromo[1,3]oxazolo[5,4-b]pyridine can be synthesized using a multi-step process involving the reaction of bromine with 1,3-oxazolo[5,4-b]pyridine. The synthesis typically utilizes a mild oxidant and involves careful control of reaction conditions to achieve high selectivity and yield. Common solvents include dichloromethane and acetic acid.

What industries use 6-Bromo[1,3]oxazolo[5,4-b]pyridine (CAS: 886372-90-3)?

6-Bromo[1,3]oxazolo[5,4-b]pyridine is used in various industries, particularly in pharmaceuticals where it is used as an intermediate for drug synthesis. Its application in polymers, sensors, and semiconductors is also being explored due to its unique chemical properties.

What precautions should be taken when handling 6-Bromo[1,3]oxazolo[5,4-b]pyridine (CAS: 886372-90-3)?

When handling 6-Bromo[1,3]oxazolo[5,4-b]pyridine, it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated fume hood to minimize exposure. Spills should be handled carefully, and spill kits should be readily available. Always refer to the Safety Data Sheet (SDS) for detailed safety information.