3-Amino-5-fluoro-6-methoxypyridine

Basic Information

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CAS Number

886372-63-0

Molecular Formula

C6H7FN2O

Molecular Weight

142.13 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

SMILES

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COC1=C(C=C(C=N1)N)F

InChI

InChI=1S/C6H7FN2O/c1-10-6-5(7)2-4(8)3-9-6/h2-3H,8H2,1H3

InChIKey

CVMLVBYTEYUXOJ-UHFFFAOYSA-N

LogP

0.8115000000000001

Topological Polar Surface Area

48.14 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

112

Synonyms & References

English

3-Amino-5-fluoro-6-methoxypyridine
3-Pyridinamine, 5-fluoro-6-methoxy-
5-fluoro-6-methoxypyridin-3-amine
QC-5174
5-FLUORO-6-METHOXY-PYRIDIN-3-YLAMINE
CVMLVBYTEYUXOJ-UHFFFAOYSA-N
5-Amino-3-fluoro-2-methoxypyridine
FCH855939
AB40818
PC402048
EN001172
AX8216185
AB0027320
W9142
ST24022672
5-fluoro-6-methoxy-pyridin-3-amine
5-Fluoro-6-methoxy-3-pyridinamine (ACI)
(5-Fluoro-6-methoxypyridin-3-yl)amine
5-Fluoro-6-methoxypyridin-3-amine
AKOS006287048
MFCD07374960
886372-63-0
DTXSID50670318
CS-W019335
SCHEMBL114939
AC-5044
3-AMINO-5-FLUORO-6-METHOXYPYRIDINE
DS-10885
J-511648

MDL Number

MFCD07374960

FAQ

What are the physical and chemical properties of 3-Amino-5-fluoro-6-methoxypyridine (CAS: 886372-63-0)?

3-Amino-5-fluoro-6-methoxypyridine is a crystalline solid with a molecular formula C8H7FN2O and a molecular weight of approximately 173.15 g/mol. It has a high solubility in water and methanol, poor solubility in hexane. The compound shows moderate reactivity, particularly towards nucleophiles. It is commonly used in organic synthesis and pharmaceuticals.

How is 3-Amino-5-fluoro-6-methoxypyridine (CAS: 886372-63-0) typically synthesized?

3-Amino-5-fluoro-6-methoxypyridine is typically synthesized through the reaction of 5-fluoro-6-methoxypyridine with an amine in the presence of a base such as sodium hydroxide. This method provides good yield and selectivity. The reaction is carried out in an organic solvent like dimethylformamide (DMF) at elevated temperatures.

What industries use 3-Amino-5-fluoro-6-methoxypyridine (CAS: 886372-63-0)?

3-Amino-5-fluoro-6-methoxypyridine is primarily used in the pharmaceutical industry for the synthesis of drug intermediates. It is also utilized in the chemical industry for the development of sensors and semiconductors due to its unique electronic properties.

What precautions should be taken when handling 3-Amino-5-fluoro-6-methoxypyridine (CAS: 886372-63-0)?

When handling 3-Amino-5-fluoro-6-methoxypyridine, it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight and heat sources. In case of a spill, it should be handled with a fume hood to avoid inhalation. Always refer to the safety data sheet (SDS) for detailed handling and safety instructions.