3,5-Bis(trifluoromethyl)phenylhydrazine

Basic Information

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CAS Number

886-35-1

Molecular Formula

C8H6F6N2

Molecular Weight

244.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

81-83 ºC

Boiling Point

196.5±40.0 ºC (760 Torr),

Density

1.497±0.06 g/cm3 (20 ºC 760 Torr),

Water Solubility

Sparingly Soluble is water.

Flash Point

72.6±27.3 ºC,

SMILES

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C1=C(C=C(C=C1C(F)(F)F)NN)C(F)(F)F

InChI

InChI=1S/C8H6F6N2/c9-7(10,11)4-1-5(8(12,13)14)3-6(2-4)16-15/h1-3,16H,15H2

InChIKey

OULWACKZBGBRNT-UHFFFAOYSA-N

LogP

3.0098000000000003

Topological Polar Surface Area

38.05 Å²

Hydrogen Bond Donor/Acceptor

3 / 2

Complexity

214

Safety Information

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GHS Hazard Pictograms

H301

H315

H319

H335

Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

3,5-Bis(trifluoromethyl)phenylhydrazine
[3,5-bis(trifluoromethyl)phenyl]hydrazine
3,5-Bis(trifluoromethyl)phenylhydrazine hydrochloride
Hydrazine,[3,5-bis(trifluoromethyl)phenyl]-
3,5-Bis(trifluoromethyl)phenylhydrazine hydrochlor
[3,5-Bis(trifluoromethyl)phenyl]hydrazine (ACI)
Hydrazine, (α,α,α,α′,α′,α′-hexafluoro-3,5-xylyl)- (8CI)
3,5-Bis(trifluoromethyl)phenyl hydrazine
1-[3,5-Bis(trifluoromethyl)phenyl]hydrazine #
SCHEMBL998165
DB-021987
(3,5-bis(trifluoromethyl)phenyl)hydrazine
FS-4414
CS-W010262
BBL012161
AKOS005254420
886-35-1
AC-4202
STK803075
1-[3,5-Bis(trifluoromethyl)phenyl]hydrazine
N11987
EN300-221650
3,5-bis-(trifluoromethyl)phenylhydrazine
Hydrazine, [3,5-bis(trifluoromethyl)phenyl]-
3,5-bis(trifluoromethyl)phenyl hydrazine
DTXSID40335106
3,5-di(Trifluoromethyl)phenylhydrazine
MFCD00051606

MDL Number

MFCD00051606

Customs Code

2928000090

FAQ

What are the physical and chemical properties of 3,5-Bis(trifluoromethyl)phenylhydrazine (CAS: 886-35-1)?

3,5-Bis(trifluoromethyl)phenylhydrazine is a crystalline solid with a molecular weight of approximately 299.09 g/mol. It has a low solubility in water but is more soluble in organic solvents like dichloromethane and acetone. This compound is known for its high reactivity and can undergo various chemical transformations, such as reduction, oxidation, and substitution reactions.

How is 3,5-Bis(trifluoromethyl)phenylhydrazine (CAS: 886-35-1) typically synthesized?

3,5-Bis(trifluoromethyl)phenylhydrazine is typically synthesized through the reduction of 3,5-bis(trifluoromethyl)phenyl isocyanate with hydrazine hydrate. Commonly used solvents include dimethylformamide (DMF) and dimethyl sulfoxide (DMSO). The reaction is often catalyzed by palladium complexes or other transition metal catalysts, leading to high yields and good selectivity.

What industries use 3,5-Bis(trifluoromethyl)phenylhydrazine (CAS: 886-35-1)?

3,5-Bis(trifluoromethyl)phenylhydrazine is used in various industries, particularly in the pharmaceutical sector for the synthesis of drug intermediates. It also finds applications in the polymer industry for improving the properties of polymers, in the sensor technology industry for developing gas sensors, and in semiconductor manufacturing for etching processes.

What precautions should be taken when handling 3,5-Bis(trifluoromethyl)phenylhydrazine (CAS: 886-35-1)?

When handling 3,5-Bis(trifluoromethyl)phenylhydrazine, it is crucial to use personal protective equipment (PPE) such as gloves, goggles, and a laboratory coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. Spills should be handled with appropriate absorbent materials and disposed of according to local hazardous waste regulations. Safety data sheets (SDS) should be consulted for detailed handling and disposal instructions.