2,3-Dichloro-5-methoxypyridine

Basic Information

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CAS Number

885168-12-7

Molecular Formula

C6H5Cl2NO

Molecular Weight

178.02 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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COC1=CC(=C(N=C1)Cl)Cl

InChI

InChI=1S/C6H5Cl2NO/c1-10-4-2-5(7)6(8)9-3-4/h2-3H,1H3

InChIKey

JQHLCLPLUWFPFE-UHFFFAOYSA-N

LogP

2.3970000000000002

Topological Polar Surface Area

22.12 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

112

Synonyms & References

English

2,3-Dichloro-5-methoxypyridine
Pyridine,2,3-dichloro-5-methoxy-
2,3-dichloro-5-methoxypyridine
2,3-Dichloro-5-methoxypyridine (ACI)
AKOS006288148
CS-0188463
E76496
SB21253
SCHEMBL5942319
BS-23967
DB-025237
885168-12-7
DTXSID30660570
MFCD08277295

MDL Number

MFCD08277295

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 2,3-Dichloro-5-methoxypyridine (CAS: 885168-12-7)?

2,3-Dichloro-5-methoxypyridine is a crystalline solid with a molecular weight of 209.01 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol and acetone. Chemically, it is relatively stable but can react with nucleophiles. It has a melting point of approximately 120-122°C.

How is 2,3-Dichloro-5-methoxypyridine (CAS: 885168-12-7) typically synthesized?

2,3-Dichloro-5-methoxypyridine is typically synthesized via the reaction of 5-methoxypyridine with chlorine gas in the presence of a catalytic amount of aluminum chloride. The reaction is selective and yields the compound with good to excellent purity.

What industries use 2,3-Dichloro-5-methoxypyridine (CAS: 885168-12-7)?

2,3-Dichloro-5-methoxypyridine is used in various industries, including pharmaceuticals for certain intermediates in drug synthesis, and in the chemical industry for its potential as a monomer in polymer synthesis. It is also explored for use in sensors and semiconductors.

What precautions should be taken when handling 2,3-Dichloro-5-methoxypyridine (CAS: 885168-12-7)?

When handling 2,3-Dichloro-5-methoxypyridine, safety goggles and gloves are required. Work should be conducted in a well-ventilated area or in a fume hood. Spills should be cleaned up with appropriate PPE, and the area should be flushed with water. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.