2,3-Dichloro-5-methoxypyridine(CAS: 885168-12-7)

2,3-Dichloro-5-methoxypyridine is a crystalline solid with a molecular weight of 209.01 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol and acetone. Chemically, it is relatively stable but can react with nucleophiles. It has a melting point of approximately 120-122°C.

2,3-Dichloro-5-methoxypyridine is typically synthesized via the reaction of 5-methoxypyridine with chlorine gas in the presence of a catalytic amount of aluminum chloride. The reaction is selective and yields the compound with good to excellent purity.

2,3-Dichloro-5-methoxypyridine is used in various industries, including pharmaceuticals for certain intermediates in drug synthesis, and in the chemical industry for its potential as a monomer in polymer synthesis. It is also explored for use in sensors and semiconductors.

When handling 2,3-Dichloro-5-methoxypyridine, safety goggles and gloves are required. Work should be conducted in a well-ventilated area or in a fume hood. Spills should be cleaned up with appropriate PPE, and the area should be flushed with water. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.