2-(Chloromethyl)-6-methylthieno[2,3-d]pyrimidin-4(1H)-one | CAS No. 878699-59-3
2-(Chloromethyl)-6-methylthieno[2,3-d]pyrimidin-4(1H)-one
Basic Information
CAS Number
878699-59-3
Molecular Formula
C8H7ClN2OS
Molecular Weight
214.68 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- DTXSID70424618
- MXAYFCHUXRRPQJ-UHFFFAOYSA-N
- 878699-59-3
- Z220564776
- MFCD01850754
- 2-(chloromethyl)-6-methyl-3H-thieno[2,3-d]pyrimidin-4-one
- 2-(CHLOROMETHYL)-6-METHYLTHIENO[2,3-D]PYRIMIDIN-4(1H)-ONE
- FT-0754536
- 2-(Chloromethyl)-6-methylthieno[2,3-d]pyrimidin-4(3H)-one
- 2-Chloromethyl-6-methyl-3H-thieno[2,3-d]pyrimidin-4-one
- SCHEMBL70147
- AKOS000742694
- 2-(chloromethyl)-6-methylthieno[2,3-d]pyrimidin-4(3H)-one(SALTDATA: FREE)
MDL Number
MFCD01850754
Customs Code
2934999090
FAQ
What are the physical and chemical properties of 2-(Chloromethyl)-6-methylthieno[2,3-d]pyrimidin-4(1H)-one (CAS: 878699-59-3)?
2-(Chloromethyl)-6-methylthieno[2,3-d]pyrimidin-4(1H)-one is a crystalline solid with a molecular weight of approximately 274.01 g/mol. It is slightly soluble in polar solvents like dimethyl sulfoxide (DMSO) and acetone. The compound exhibits good reactivity towards nucleophiles, particularly in the chloromethyl group, making it suitable for various chemical transformations.
How is 2-(Chloromethyl)-6-methylthieno[2,3-d]pyrimidin-4(1H)-one (CAS: 878699-59-3) typically synthesized?
2-(Chloromethyl)-6-methylthieno[2,3-d]pyrimidin-4(1H)-one can be synthesized via the condensation of 2-chloroacetyl chloride with 6-methylthieno[2,3-d]pyrimidin-4-one. The reaction is typically catalyzed by a Lewis acid such as aluminum chloride and proceeds with good yields (up to 90%). Selectivity towards the desired product is maintained, making this a reliable route for synthesis.
What industries use 2-(Chloromethyl)-6-methylthieno[2,3-d]pyrimidin-4(1H)-one (CAS: 878699-59-3)?
2-(Chloromethyl)-6-methylthieno[2,3-d]pyrimidin-4(1H)-one finds applications in the pharmaceutical and polymer industries. It is used as an intermediate in the synthesis of medicinal compounds and as a building block in the development of polymeric materials with specific properties such as conductivity and mechanical strength.
What precautions should be taken when handling 2-(Chloromethyl)-6-methylthieno[2,3-d]pyrimidin-4(1H)-one (CAS: 878699-59-3)?
When handling 2-(Chloromethyl)-6-methylthieno[2,3-d]pyrimidin-4(1H)-one, proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. Work should be conducted in a well-ventilated fume hood to minimize exposure. Spills should be cleaned up immediately using absorbent materials, and the area should be flushed with water. Refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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