2,3-Dibromo-5-fluoropyridine

Basic Information

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CAS Number

878207-82-0

Molecular Formula

C5H2Br2FN

Molecular Weight

254.88 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

38-41°C

Boiling Point

222℃ at 760 mmHg

SMILES

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Fc1cnc(Br)c(Br)c1

InChI

InChI=1S/C5H2Br2FN/c6-4-1-3(8)2-9-5(4)7/h1-2H

InChIKey

ASHZMYYXNMJUDZ-UHFFFAOYSA-N

LogP

2.7457000000000003

Topological Polar Surface Area

12.89 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

101

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

2,3-Dibromo-5-fluoropyridine
2,3-Dibromo-5-fluoro-pyridine
2,3,5,6-TETRAFLUOROPYRIDINE-4-ACETIC ACID
Pyridine,2,3-dibromo-5-fluoro
Pyridine, 2,3-dibromo-5-fluoro-
PubChem21379
KSC447Q5R
ASHZMYYXNMJUDZ-UHFFFAOYSA-N
Pyridine,2,3-dibromo-5-fluoro-
BCP22118
PC9196
SBB101511
AM62434
VP10900
FCH1389275
AS04726
BC004640
ST2403593
AX8065364
AB0027211
W9021
2,3-Dibromo-5-fluoropyridine (ACI)

MDL Number

MFCD08532501

FAQ

What are the physical and chemical properties of 2,3-Dibromo-5-fluoropyridine (CAS: 878207-82-0)?

2,3-Dibromo-5-fluoropyridine is a crystalline solid with a molecular weight of approximately 267.02 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. This compound is highly reactive, especially towards nucleophiles and reducing agents.

How is 2,3-Dibromo-5-fluoropyridine (CAS: 878207-82-0) typically synthesized?

2,3-Dibromo-5-fluoropyridine is usually synthesized via a bromination reaction of 5-fluoropyridine with bromine in the presence of a Lewis acid catalyst such as iron(III) bromide. The reaction yields a high purity product with good selectivity and reasonable yield.

What industries use 2,3-Dibromo-5-fluoropyridine (CAS: 878207-82-0)?

2,3-Dibromo-5-fluoropyridine is used in the pharmaceutical industry as an intermediate for the synthesis of certain drugs. It also finds applications in polymer chemistry as a brominated flame retardant and in the production of sensors and semiconductors.

What precautions should be taken when handling 2,3-Dibromo-5-fluoropyridine (CAS: 878207-82-0)?

When handling 2,3-Dibromo-5-fluoropyridine, wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work in a fume hood to minimize exposure to vapors. In case of a spill, immediately clean up the area with appropriate absorbent materials and ensure proper disposal. Refer to the Safety Data Sheet (SDS) for detailed handling and disposal procedures.