2,3-Dibromo-5-fluoropyridine(CAS: 878207-82-0)

2,3-Dibromo-5-fluoropyridine is a crystalline solid with a molecular weight of approximately 267.02 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. This compound is highly reactive, especially towards nucleophiles and reducing agents.

2,3-Dibromo-5-fluoropyridine is usually synthesized via a bromination reaction of 5-fluoropyridine with bromine in the presence of a Lewis acid catalyst such as iron(III) bromide. The reaction yields a high purity product with good selectivity and reasonable yield.

2,3-Dibromo-5-fluoropyridine is used in the pharmaceutical industry as an intermediate for the synthesis of certain drugs. It also finds applications in polymer chemistry as a brominated flame retardant and in the production of sensors and semiconductors.

When handling 2,3-Dibromo-5-fluoropyridine, wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work in a fume hood to minimize exposure to vapors. In case of a spill, immediately clean up the area with appropriate absorbent materials and ensure proper disposal. Refer to the Safety Data Sheet (SDS) for detailed handling and disposal procedures.