2-Methyl-2-propanyl 4-[(cyclopropylamino)methyl]-1-piperidinecarboxylate | CAS No. 877859-58-0

2-Methyl-2-propanyl 4-[(cyclopropylamino)methyl]-1-piperidinecarboxylate

Basic Information

CAS Number

877859-58-0

Molecular Formula

C14H26N2O2

Molecular Weight

254.37 g/mol

AD

Basic Physical Properties

Density

1.05

CC(C)(C)OC(=O)N1CCC(CC1)CNC2CC2

InChI

InChI=1S/C14H26N2O2/c1-14(2,3)18-13(17)16-8-6-11(7-9-16)10-15-12-4-5-12/h11-12,15H,4-10H2,1-3H3

InChIKey

CZXMVDICWYFHTA-UHFFFAOYSA-N

LogP

2.3855000000000004

Topological Polar Surface Area

41.57000000000001 Ų

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

287

Synonyms & References

English

  • SY267112
  • FT-0688653
  • A1-15607
  • 877859-58-0
  • CKB85958
  • tert-Butyl 4-[(cyclopropylamino)methyl]piperidine-1-carboxylate
  • CS-0326143
  • 4-Cyclopropylaminomethyl-piperidine-1-carboxylic acid tert-butyl ester
  • SB43880
  • SCHEMBL2130795
  • DTXSID60586370
  • AM101453
  • CZXMVDICWYFHTA-UHFFFAOYSA-N
  • MFCD09836819
  • tert-Butyl4-((cyclopropylamino)methyl)piperidine-1-carboxylate
  • AKOS005067700
  • 1-Boc-4-[(cyclopropylamino)methyl]piperidine
  • tert-Butyl 4-((cyclopropylamino)methyl)piperidine-1-carboxylate
  • N-[(1-Boc-4-piperidyl)methyl]cyclopropanamine
  • F79438
  • 1-PIPERIDINECARBOXYLIC ACID, 4-[(CYCLOPROPYLAMINO)METHYL]-, 1,1-DIMETHYLETHYL ESTER
  • tert-butyl 4-[(cyclopropylamino)methyl]piperidine-1-carboxylate

MDL Number

MFCD09836819

FAQ

What are the physical and chemical properties of 2-Methyl-2-propanyl 4-[(cyclopropylamino)methyl]-1-piperidinecarboxylate (CAS: 877859-58-0)?

2-Methyl-2-propanyl 4-[(cyclopropylamino)methyl]-1-piperidinecarboxylate is a colorless to white crystalline solid with a molecular weight of approximately 288.39 g/mol. It has a low solubility in water but is soluble in organic solvents such as methanol and ethanol. The compound exhibits moderate reactivity, showing basic properties due to the presence of the amino group and piperidine ring, and is stable under normal conditions but should be stored in a dry, fume hood to prevent moisture absorption.

How is 2-Methyl-2-proanyl 4-[(cyclopropylamino)methyl]-1-piperidinecarboxylate (CAS: 877859-58-0) typically synthesized?

2-Methyl-2-proanyl 4-[(cyclopropylamino)methyl]-1-piperidinecarboxylate can be synthesized by reacting cyclopropylamine with 2-methyl-2-proanylmethyl chloroacetate followed by piperidine addition. The reaction typically requires a base such as triethylamine and is conducted at room temperature. The synthetic route provides good yield and selectivity, making it a suitable method for preparing this complex compound.

What industries use 2-Methyl-2-proanyl 4-[(cyclopropylamino)methyl]-1-piperidinecarboxylate (CAS: 877859-58-0)?

2-Methyl-2-proanyl 4-[(cyclopropylamino)methyl]-1-piperidinecarboxylate finds applications in pharmaceuticals, where it serves as an intermediate in drug synthesis. It is also used in polymer chemistry for synthesizing advanced materials and in chemical sensors due to its functional groups that can interact with various analytes.

What precautions should be taken when handling 2-Methyl-2-proanyl 4-[(cyclopropylamino)methyl]-1-piperidinecarboxylate (CAS: 877859-58-0)?

When handling 2-Methyl-2-proanyl 4-[(cyclopropylamino)methyl]-1-piperidinecarboxylate, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. This compound should be stored in a fume hood to prevent exposure to moisture and air. Spills should be cleaned up immediately using appropriate absorbent materials, and the area should be well ventilated. Safety data sheets (SDS) should be consulted for detailed handling and disposal guidelines.

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