1-(3-Fluoro-2-pyridinyl)ethanone

Basic Information

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CAS Number

87674-20-2

Molecular Formula

C7H6FNO

Molecular Weight

139.13 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Boiling Point

179.7℃ at 760 mmHg

SMILES

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CC(=O)C1=C(C=CC=N1)F

InChI

InChI=1S/C7H6FNO/c1-5(10)7-6(8)3-2-4-9-7/h2-4H,1H3

InChIKey

CCZMVVFNNQQTFC-UHFFFAOYSA-N

LogP

1.4233

Topological Polar Surface Area

29.96 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

138

Synonyms & References

English

1-(3-FLUOROPYRIDIN-2-YL)ETHAN-1-ONE
87674-20-2
AKOS006295108
SCHEMBL1812108
CCZMVVFNNQQTFC-UHFFFAOYSA-N
SY022346
CS-W021536
P10386
1-(3-fluoropyridin-2-yl)ethanone
J-503140
MFCD06659495
1-(3-Fluoro-2-pyridinyl)ethanone
1-(3-FLUORO-2-PYRIDINYL)-ETHANONE
PB26212
AM85388
AC-33325
2-ACETYL-3-FLUOROPYRIDINE
FT-0650020
DTXSID00520591
DS-12734
EN300-177396
ETHANONE, 1-(3-FLUORO-2-PYRIDINYL)-
2-Acetyl-3-fluoropyridine
1-(3-fluoropyridin-2-yl)ethan-1-one
1-(3-Fluoro-2-pyridinyl)ethanone (ACI)
1-(3-Fluoropyridin-2-yl)ethan-1-one

MDL Number

MFCD06659495

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 1-(3-Fluoro-2-pyridinyl)ethanone (CAS: 87674-20-2)?

1-(3-Fluoro-2-pyridinyl)ethanone (CAS: 87674-20-2) is a white crystalline solid with a molecular weight of approximately 166.14 g/mol. It is sparingly soluble in water but soluble in organic solvents like ethanol and acetone. Chemically, it is reactive, particularly towards nucleophiles and reducing agents.

How is 1-(3-Fluoro-2-pyridinyl)ethanone (CAS: 87674-20-2) typically synthesized?

1-(3-Fluoro-2-pyridinyl)ethanone can be synthesized via a nucleophilic substitution reaction, where a fluoro-pyridine derivative reacts with an ethyl ketone under basic conditions. Commonly, potassium carbonate is used as a base, and the reaction is typically conducted in an aprotic solvent like acetonitrile.

What industries use 1-(3-Fluoro-2-pyridinyl)ethanone (CAS: 87674-20-2)?

1-(3-Fluoro-2-pyridinyl)ethanone (CAS: 87674-20-2) finds applications in the pharmaceutical industry for the synthesis of certain drugs, particularly those involving pyridine derivatives. It is also used in the chemical manufacturing sector for the production of other organic compounds and in research for its unique chemical properties.

What precautions should be taken when handling 1-(3-Fluoro-2-pyridinyl)ethanone (CAS: 87674-20-2)?

When handling 1-(3-Fluoro-2-pyridinyl)ethanone (CAS: 87674-20-2), it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The substance should be stored in a cool, dry place away from sources of heat and ignition. Spills should be cleaned up using appropriate methods, and the material safety data sheet (MSDS) should be consulted for detailed handling and disposal instructions.