1-(3-Fluoro-2-pyridinyl)ethanone(CAS: 87674-20-2)

1-(3-Fluoro-2-pyridinyl)ethanone (CAS: 87674-20-2) is a white crystalline solid with a molecular weight of approximately 166.14 g/mol. It is sparingly soluble in water but soluble in organic solvents like ethanol and acetone. Chemically, it is reactive, particularly towards nucleophiles and reducing agents.

1-(3-Fluoro-2-pyridinyl)ethanone can be synthesized via a nucleophilic substitution reaction, where a fluoro-pyridine derivative reacts with an ethyl ketone under basic conditions. Commonly, potassium carbonate is used as a base, and the reaction is typically conducted in an aprotic solvent like acetonitrile.

1-(3-Fluoro-2-pyridinyl)ethanone (CAS: 87674-20-2) finds applications in the pharmaceutical industry for the synthesis of certain drugs, particularly those involving pyridine derivatives. It is also used in the chemical manufacturing sector for the production of other organic compounds and in research for its unique chemical properties.

When handling 1-(3-Fluoro-2-pyridinyl)ethanone (CAS: 87674-20-2), it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The substance should be stored in a cool, dry place away from sources of heat and ignition. Spills should be cleaned up using appropriate methods, and the material safety data sheet (MSDS) should be consulted for detailed handling and disposal instructions.