1-[(Aminooxy)methyl]-4-methoxybenzene hydrochloride (1:1)

Basic Information

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CAS Number

876-33-5

Molecular Formula

C8H12ClNO2

Molecular Weight

189.64 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

209-211°C

SMILES

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NOCc1ccc(cc1)OC.Cl

InChI

InChI=1S/C8H11NO2.ClH/c1-10-8-4-2-7(3-5-8)6-11-9;/h2-5H,6,9H2,1H3;1H

InChIKey

DHEZQYZJFCIQQA-UHFFFAOYSA-N

LogP

1.5072999999999999

Topological Polar Surface Area

44.480000000000004 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

100

Safety Information

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Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

O-(4-Methoxybenzyl)hydroxylamine hydrochloride
1-[(Aminooxy)methyl]-4-methoxybenzenehydrochloride
1-[(AMMONIOOXY)METHYL]-4-METHOXYBENZENE CHLORIDE
Hydroxylamine,O-[(4-methoxyphenyl)methyl]-, hydrochloride (1:1)
O-[(4-methoxyphenyl)methyl]Hydroxylamine hydrochloride
1-[(Aminooxy)methyl]-4-methoxybenzene hydrochloride
O-4-Methoxybenzylhydroxylamine hydrochloride
Hydroxylamine, O-(p-methoxybenzyl)-, hydrochloride
Hydroxylamine, O-[(4-methoxyphenyl)methyl]-, hydrochloride
O-(4-Methoxy-benzyl)-hydroxylamine hydrochloride
O-(4-METHOXYBENZYL)
Benzyloxyamine, p-methoxy-, hydrochloride (7CI)
Hydroxylamine, O-(p-methoxybenzyl)-, hydrochloride (8CI)
Hydroxylamine, O-[(4-methoxyphenyl)methyl]-, hydrochloride (9CI)
4-Methoxybenzyloxyamine hydrochloride

MDL Number

MFCD01114582

Customs Code

2922299090

FAQ

What are the physical and chemical properties of 1-[(Aminooxy)methyl]-4-methoxybenzene hydrochloride (CAS: 876-33-5)?

1-[(Aminooxy)methyl]-4-methoxybenzene hydrochloride (CAS: 876-33-5) has a crystalline form with a molecular weight of approximately 278.68 g/mol. It is slightly soluble in water but soluble in organic solvents such as methanol and ethanol. Chemically, it is less reactive, making it suitable for various applications. Its solubility and reactivity make it useful in chemical synthesis and pharmaceutical formulations.

How is 1-[(Aminooxy)methyl]-4-methoxybenzene hydrochloride (CAS: 876-33-5) typically synthesized?

1-[(Aminooxy)methyl]-4-methoxybenzene hydrochloride is typically synthesized via the reaction of aminooxyacetic acid and 4-methoxybenzene, followed by hydrochloric acid treatment. This process is known for its good yield and selectivity. Suitable catalysts include various amine bases, and the reaction conditions are optimized for high efficiency.

What industries use 1-[(Aminooxy)methyl]-4-methoxybenzene hydrochloride (CAS: 876-33-5)?

1-[(Aminooxy)methyl]-4-methoxybenzene hydrochloride (CAS: 876-33-5) is used in pharmaceuticals for its potential as an intermediate in drug synthesis, polymers for its stability, and sensors for its reactivity. It also finds application in the semiconductor industry due to its chemical properties.

What precautions should be taken when handling 1-[(Aminooxy)methyl]-4-methoxybenzene hydrochloride (CAS: 876-33-5)?

When handling 1-[(Aminooxy)methyl]-4-methoxybenzene hydrochloride (CAS: 876-33-5), it is essential to wear personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work in a well-ventilated area or fume hood to avoid inhalation. Follow proper spill handling procedures and ensure that safety data sheets (SDS) are readily available for reference. Storage should be in a cool, dry place away from direct sunlight and heat sources.