Compound Q&A

How is 1-[(Aminooxy)methyl]-4-methoxybenzene hydrochloride (CAS: 876-33-5) typically synthesized?

Answer

1-[(Aminooxy)methyl]-4-methoxybenzene hydrochloride (1:1)
1-[(Aminooxy)methyl]-4-methoxybenzene hydrochloride is typically synthesized via the reaction of aminooxyacetic acid and 4-methoxybenzene, followed by hydrochloric acid treatment. This process is known for its good yield and selectivity. Suitable catalysts include various amine bases, and the reaction conditions are optimized for high efficiency.

About

CAS No 876-33-5
English Name 1-[(Aminooxy)methyl]-4-methoxybenzene hydrochloride (1:1)
Molecular Formula C8H12ClNO2
Molecular Weight 189.64 g/mol
SMILES NOCc1ccc(cc1)OC.Cl
InChIKey DHEZQYZJFCIQQA-UHFFFAOYSA-N
Last Updated: 2025-09-25 13:48

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