(4R,5S)-5-[3,5-Bis(trifluoromethyl)phenyl]-4-methyl-1,3-oxazolidin-2-one | CAS No. 875444-10-3
(4R,5S)-5-[3,5-Bis(trifluoromethyl)phenyl]-4-methyl-1,3-oxazolidin-2-one
Basic Information
CAS Number
875444-10-3
Molecular Formula
C12H9F6NO2
Molecular Weight
313.2 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- (4R,5S)-5-[3,5-Bis(Trifluoromethyl)-phenyl]-4-methyl-oxazolidin-2-one
- 875444-10-3
- (4R,5S)-5-[3,5-bis(trifluoromethyl)phenyl]-4-methyl-1,3-oxazolidin-2-one
- (4R,5S)-5-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]-4-METHYL-OXAZOLIDIN-2-ONE
- 2-Oxazolidinone, 5-[3,5-bis(trifluoromethyl)phenyl]-4-methyl-, (4R,5S)-
- CS-0053179
- SCHEMBL531518
- AS-34950
- (4R,5S)-5-(3,5-bis-trifluoromethyl-phenyl)-4-methyl-oxazolidin-2-one
- MFCD16294182
- J-501474
- (4R,5S)-5-(3,5-Bis(trifluoromethyl)phenyl)-4-methyloxazolidin-2-one
- AKOS015949285
- DTXSID90693647
- (4R,5S)-5-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]-4-METHYL-1,3-OXAZOLIDIN-2-ONE
- C12H9F6NO2
- OHIDCVTXTYVGRO-MLUIRONXSA-N
- PB21375
- AK171894
- Y4434
- (4R,5S)-5-[3,5-Bis(tr
- (4R,5S)-5-[3,5-bis(trifluoromethyl)phenyl]-4-methyl-oxazolidin-2-one
MDL Number
MFCD16294182
Customs Code
2934999090
FAQ
What are the physical and chemical properties of (4R,5S)-5-[3,5-Bis(trifluoromethyl)phenyl]-4-methyl-1,3-oxazolidin-2-one (CAS: 875444-10-3)?
(4R,5S)-5-[3,5-Bis(trifluoromethyl)phenyl]-4-methyl-1,3-oxazolidin-2-one (CAS: 875444-10-3) is a white crystalline solid. It has a high molecular weight of approximately 412.2 g/mol. The compound is poorly soluble in water but soluble in organic solvents like methanol and ethyl acetate. It exhibits good stability under neutral pH conditions and has limited reactivity under standard conditions. It is characterized by its unique electronic properties due to the trifluoromethyl groups, which make it suitable for various applications in chemistry.
How is (4R,5S)-5-[3,5-Bis(trifluoromethyl)phenyl]-4-methyl-1,3-oxazolidin-2-one (CAS: 875444-10-3) typically synthesized?
(4R,5S)-5-[3,5-Bis(trifluoromethyl)phenyl]-4-methyl-1,3-oxazolidin-2-one (CAS: 875444-10-3) is typically synthesized via a multistep process involving the protection of an alcohol, followed by the formation of an oxazolidinone ring. The synthesis involves the use of protecting agents such as tert-butyldimethylsilyl chloride and catalytic amounts of trifluoroacetic acid. The yield of the final product is around 65-70%, and the purity is enhanced through recrystallization.
What industries use (4R,5S)-5-[3,5-Bis(trifluoromethyl)phenyl]-4-methyl-1,3-oxazolidin-2-one (CAS: 875444-10-3)?
(4R,5S)-5-[3,5-Bis(trifluoromethyl)phenyl]-4-methyl-1,3-oxazolidin-2-one (CAS: 875444-10-3) is used in the pharmaceutical industry for the development of drugs with specific biological activities. It is also applied in the polymer industry for the synthesis of novel materials with unique electronic and mechanical properties. Additionally, it is of interest in the sensor and semiconductor industries due to its unique electronic properties.
What precautions should be taken when handling (4R,5S)-5-[3,5-Bis(trifluoromethyl)phenyl]-4-methyl-1,3-oxazolidin-2-one (CAS: 875444-10-3)?
When handling (4R,5S)-5-[3,5-Bis(trifluoromethyl)phenyl]-4-methyl-1,3-oxazolidin-2-one (CAS: 875444-10-3), it is essential to use proper personal protective equipment (PPE) including gloves, goggles, and a lab coat. This compound should be handled in a well-ventilated area, preferably under a fume hood. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for further safety information and emergency procedures.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
You might also like
Compound Q&A
What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?
6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...
21889-89-46-Methyl-7-oxabicycl...
Compound Q&A
What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?
4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...
906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A
What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?
2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...
49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A
What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?
2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...
24783-42-42-(6-Chloro-2-pyridi...
Compound Q&A
What is 2-Oxopropanamide (CAS: 631-66-3)?
2-Oxopropanamide, also known as 2-aminoacrylic acid, is a chemical compound with...
631-66-32-Oxopropanamide
Compound Q&A
What is 2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CAS: 1289040-88-5)?
2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CA...
1289040-88-52-Methyl-2-propanyl ...
Compound Q&A
What is NAMPT inhibitor-linker 1 (CAS: 2241019-57-6)?
NAMPT inhibitor-linker 1 (CAS: 2241019-57-6) is a chemical compound designed as ...
2241019-57-6NAMPT inhibitor-link...
Compound Q&A
What is (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS: 1310404-58-0)?
It is a chemical compound with the structure (2-(2,2,2-Trifluoroacetyl)pyridin-4...
1310404-58-0(2-(2,2,2-Trifluoroa...
Compound Q&A
What is 1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS: 794568-90-4)?
1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,...
794568-90-41-(2-Chlorophenyl)-6...
Compound Q&A
What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?
Vinyl(chloromethyl)dimethoxysilane is an organosilicon compound with the molecul...
1314981-48-0Vinyl(chloromethyl)d...
![(4R,5S)-5-[3,5-Bis(trifluoromethyl)phenyl]-4-methyl-1,3-oxazolidin-2-one — Shanghai Yuyeh Biotechnology Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce9f132b2de6e8e95a48fe/67ce9f132b2de6e8e95a48fe-logo.webp){kind=logo}
![(4R,5S)-5-[3,5-Bis(trifluoromethyl)phenyl]-4-methyl-1,3-oxazolidin-2-one — Jin Jinle (Hunan) Chemical Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce76192b2de6e8e95a464e/67ce76192b2de6e8e95a464e-logo.webp){kind=logo}
![(4R,5S)-5-[3,5-Bis(trifluoromethyl)phenyl]-4-methyl-1,3-oxazolidin-2-one — Shanghai Jixiang Biotechnology Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce6f4d2b2de6e8e95a45bf/67ce6f4d2b2de6e8e95a45bf-logo.webp){kind=logo}
![(4R,5S)-5-[3,5-Bis(trifluoromethyl)phenyl]-4-methyl-1,3-oxazolidin-2-one — Shanghai Yinxin Laboratory Equipment Co., Ltd.](https://static.chemtradehub.com/suppliers/67cdd97a57537e5c8069adfb/67cdd97a57537e5c8069adfb-logo.webp){kind=logo}