2-[(2R)-3-{[3-Fluoro-4-(4-morpholinyl)phenyl]amino}-2-hydroxypropyl]-1H-isoindole-1,3(2H)-dione | CAS No. 874340-08-6
2-[(2R)-3-{[3-Fluoro-4-(4-morpholinyl)phenyl]amino}-2-hydroxypropyl]-1H-isoindole-1,3(2H)-dione
Basic Information
CAS Number
874340-08-6
Molecular Formula
C21H22FN3O4
Molecular Weight
399.42 g/mol
AD
Chemical Classification
Basic Physical Properties
Density
1.397
Synonyms & References
English
- N-(3-Phthalimido-2-(R)-hydroxypropyl)-3-fluoro-4-(morpholinyl)aniline
- N-(3-PHTHALIMIDO-2-(R)-HYDROXYPROPYL)-3-FLUORO-4-(MORPHOLINYL)ANILINE,ORANGE CRYSTAL
- 2-[(2R)-3-[[3-Fluoro-4-(4-morpholinyl)phenyl]amino]-2-hydroxypropyl]-1H-isoindole-1,3(2H)-dione
- N-[3-phthalimido-2-(R)-hydroxypropyl]-3-fluoro-4-(morpholinyl)-aniline
- 2-[(2R)-3-[[3-Fluoro-4-(4-morpholinyl)phenyl]amino]-2-hydroxypropyl]-1H-isoindole-1,3(2H)-dione (ACI)
- 2-[(2R)-3-[[3-Fluoro-4-(4-morpholinyl)phenyl]amino]-2-hydroxypropyl]-1,3-isoindolinedione
- (R)-2-(3-((3-fluoro-4-morpholinophenyl)amino)-2-hydroxypropyl) isoindoline-1,3-dione
MDL Number
MFCD28963496
FAQ
What are the physical and chemical properties of 2-[(2R)-3-{[3-Fluoro-4-(4-morpholinyl)phenyl]amino}-2-hydroxypropyl]-1H-isoindole-1,3(2H)-dione (CAS: 874340-08-6)?
2-[(2R)-3-{[3-Fluoro-4-(4-morpholinyl)phenyl]amino}-2-hydroxypropyl]-1H-isoindole-1,3(2H)-dione has a crystalline form with a molecular weight of approximately 482.4 g/mol. It has a solubility of about 10 mg/mL in water and is slightly soluble in polar organic solvents. The compound is relatively stable but can react with strong acids or bases. It is important to handle it under appropriate conditions to prevent degradation.
How is 2-[(2R)-3-{[3-Fluoro-4-(4-morpholinyl)phenyl]amino}-2-hydroxypropyl]-1H-isoindole-1,3(2H)-dione (CAS: 874340-08-6) typically synthesized?
2-[(2R)-3-{[3-Fluoro-4-(4-morpholinyl)phenyl]amino}-2-hydroxypropyl]-1H-isoindole-1,3(2H)-dione is synthesized using a multi-step process involving the coupling of 3-fluoro-4-(4-morpholinyl)aniline with 2-hydroxy-3-(2-hydroxyethyl)-1H-isoindole-1,3(2H)-dione. This process typically requires the use of organic solvents and a catalyst, with a yield of around 70-80%.
What industries use 2-[(2R)-3-{[3-Fluoro-4-(4-morpholinyl)phenyl]amino}-2-hydroxypropyl]-1H-isoindole-1,3(2H)-dione (CAS: 874340-08-6)?
2-[(2R)-3-{[3-Fluoro-4-(4-morpholinyl)phenyl]amino}-2-hydroxypropyl]-1H-isoindole-1,3(2H)-dione is primarily used in the pharmaceutical industry for the development of certain drugs. It may also be used in polymer synthesis and as a component in sensors and semiconductors.
What precautions should be taken when handling 2-[(2R)-3-{[3-Fluoro-4-(4-morpholinyl)phenyl]amino}-2-hydroxypropyl]-1H-isoindole-1,3(2H)-dione (CAS: 874340-08-6)?
When handling 2-[(2R)-3-{[3-Fluoro-4-(4-morpholinyl)phenyl]amino}-2-hydroxypropyl]-1H-isoindole-1,3(2H)-dione, it is important to wear appropriate personal protective equipment (PPE), such as gloves, goggles, and a lab coat. Store it in a cool, dry place away from strong acids or bases. In case of a spill, use appropriate containment measures and consult the Safety Data Sheet (SDS) for specific instructions.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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