Compound Q&A
How is 2-[(2R)-3-{[3-Fluoro-4-(4-morpholinyl)phenyl]amino}-2-hydroxypropyl]-1H-isoindole-1,3(2H)-dione (CAS: 874340-08-6) typically synthesized?
Answer
![2-[(2R)-3-{[3-Fluoro-4-(4-morpholinyl)phenyl]amino}-2-hydroxypropyl]-1H-isoindole-1,3(2H)-dione](https://static.chemtradehub.com/structs/874/874340-08-6-e557.webp "2-[(2R)-3-{[3-Fluoro-4-(4-morpholinyl)phenyl]amino}-2-hydroxypropyl]-1H-isoindole-1,3(2H)-dione")
2-[(2R)-3-{[3-Fluoro-4-(4-morpholinyl)phenyl]amino}-2-hydroxypropyl]-1H-isoindole-1,3(2H)-dione is synthesized using a multi-step process involving the coupling of 3-fluoro-4-(4-morpholinyl)aniline with 2-hydroxy-3-(2-hydroxyethyl)-1H-isoindole-1,3(2H)-dione. This process typically requires the use of organic solvents and a catalyst, with a yield of around 70-80%.
About
CAS No
874340-08-6
English Name
2-[(2R)-3-{[3-Fluoro-4-(4-morpholinyl)phenyl]amino}-2-hydroxypropyl]-1H-isoindole-1,3(2H)-dione
Molecular Formula
C21H22FN3O4
Molecular Weight
399.42 g/mol
SMILES
O=C1N(C[C@H](O)CNC2=CC=C(N3CCOCC3)C(F)=C2)C(C4=C1C=CC=C4)=O
InChIKey
UVDYUDNYSNKZRV-OAHLLOKOSA-N
Last Updated: 2025-12-28 10:59
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