(2R,3S)-2-Amino-3-hydroxy-4-methylpentanoic acid

Basic Information

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CAS Number

87421-23-6

Molecular Formula

C6H13NO3

Molecular Weight

147.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Physical Properties

Melting Point

205-208 ºC

Boiling Point

267.28°C (rough estimate)

Density

1.2006 (rough estimate)

Refractive Index

1.4240 (estimate)

Specific Rotation

-19.4 º (c=2, 6N HCl 25 ºC)

SMILES

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CC(C)[C@H](O)[C@@H](N)C(O)=O

InChI

InChI=1S/C6H13NO3/c1-3(2)5(8)4(7)6(9)10/h3-5,8H,7H2,1-2H3,(H,9,10)/t4-,5+/m1/s1

InChIKey

ZAYJDMWJYCTABM-UHNVWZDZSA-N

LogP

-0.5848

Topological Polar Surface Area

83.55000000000001 Å²

Hydrogen Bond Donor/Acceptor

4 / 4

Complexity

124

Synonyms & References

English

(2R,3S)-2-Amino-3-hydroxy-4-methylpentanoic acid
D(-)-threo-3-Hydroxyleucine
(2R,3S)-β-Hydroxyleucine
(2R,3S)-(-)-2-amino-3-hydroxy-4-methylpentanoic acid
(3S)-3-Hydroxy-D-leucine (ACI)
D-Leucine, 3-hydroxy-, threo- (ZCI)
D-threo-β-Hydroxyleucine

MDL Number

MFCD00142970

FAQ

What is (2R,3S)-2-Amino-3-hydroxy-4-methylpentanoic acid (CAS: 87421-23-6)?

(2R,3S)-2-Amino-3-hydroxy-4-methylpentanoic acid, also known as N-(2-amino-3-hydroxy-4-methylbutanoyl)glycine, is a chiral amino acid. It has the chemical formula C7H15NO3 and features a hydroxyl group, an amino group, and a methyl group attached to a five-carbon backbone. This compound is important in pharmaceuticals and research due to its structural properties.

What are the main uses of (2R,3S)-2-Amino-3-hydroxy-4-methylpentanoic acid (CAS: 87421-23-6)?

(2R,3S)-2-Amino-3-hydroxy-4-methylpentanoic acid is primarily used in pharmaceutical research and development. It serves as a molecular building block for developing new drugs and in the synthesis of chiral compounds. Additionally, it is used in the preparation of chiral ligands and as a standard reagent in analytical chemistry.

Is (2R,3S)-2-Amino-3-hydroxy-4-methylpentanoic acid (CAS: 87421-23-6) safe?

When handled properly, (2R,3S)-2-Amino-3-hydroxy-4-methylpentanoic acid is considered safe. However, appropriate protective measures should be taken, including wearing gloves and protective eyewear. It is important to avoid contact with skin and eyes and to store the compound in a cool, dry place away from direct sunlight and heat sources.

How should (2R,3S)-2-Amino-3-hydroxy-4-methylpentanoic acid (CAS: 87421-23-6) be stored?

(2R,3S)-2-Amino-3-hydroxy-4-methylpentanoic acid should be stored in a tightly sealed container, away from direct sunlight and heat sources. Maintain a temperature range between 15°C and 25°C (59°F and 77°F) to prevent degradation. Keep the compound in a dry environment to avoid moisture exposure, which can affect its stability.