Omecamtiv mecarbil

Basic Information

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CAS Number

873697-71-3

Molecular Formula

C20H24FN5O3

Molecular Weight

401.43 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

180℃

SMILES

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COC(=O)N1CCN(CC1)Cc1cccc(c1F)NC(=O)Nc1ccc(nc1)C

InChI

InChI=1S/C20H24FN5O3/c1-14-6-7-16(12-22-14)23-19(27)24-17-5-3-4-15(18(17)21)13-25-8-10-26(11-9-25)20(28)29-2/h3-7,12H,8-11,13H2,1-2H3,(H2,23,24,27)

InChIKey

RFUBTTPMWSKEIW-UHFFFAOYSA-N

LogP

3.057120000000001

Topological Polar Surface Area

86.8 Å²

Hydrogen Bond Donor/Acceptor

2 / 8

Synonyms & References

English

1-Piperazinecarboxylic acid,4-[[2-fluoro-3-[[[(6-methyl-3-pyridinyl)amino]carbonyl]amino]phenyl]methyl]-, methyl ester
Omecamtiv mecarbil (CK-1827452)
1-Piperazinecarboxylic acid,4-[[2-fluoro-3-[[[(6-methyl-3-pyridinyl)amino]carbonyl]amino]pheny...
CK 1827452
CK-1827452
methyl 4-[(2-fluoro-3-{[(6-methylpyridin-3-yl)carbamoyl]amino}phenyl)methyl] piperazine-1-carboxylate
methyl 4-[[2-fluoro-3-[(6-methylpyridin-3-yl)carbamoylamino]phenyl]methyl]piperazine-1-carboxylate
Methyl 4-[[2-fluoro-3-[N'-(6-methylpyridin-3-yl)ureido]phenyl]methyl]piperazine-1-carboxylate
Omecamtiv mecarbil(CK1827452)
Omecamtiv mecarbil
Methyl 4-[[2-fluoro-3-[N′-(6-methylpyridin-3-yl)ureido]phenyl]methyl]piperazine-1-carboxylate

MDL Number

MFCD18633260

FAQ

What regulatory guidelines apply to Omecamtiv mecarbil (CAS: 873697-71-3)?

Omecamtiv mecarbil (CAS: 873697-71-3) falls under various regulatory guidelines, including GHS classification for handling and storage, REACH regulations in the EU for registration, evaluation, and authorization, and FDA/EPA requirements for drug approval and safety assessment. It is crucial to adhere to these guidelines to ensure safe and lawful handling.

Are there alternatives to Omecamtiv mecarbil (CAS: 873697-71-3) in synthesis?

There are several alternatives to Omecamtiv mecarbil (CAS: 873697-71-3) in synthesis, such as isomers and analogs like omecamtiv mecarbil propionate, which can be used based on specific synthetic requirements. Common alternative reagents include various catalysts and solvents that can facilitate the synthesis process with different efficiency and selectivity.

What is the market or research trend for Omecamtiv mecarbil (CAS: 873697-71-3)?

The market for Omecamtiv mecarbil (CAS: 873697-71-3) is growing due to its potential as a cardiac contractility enhancer for treating heart failure. Research trends are focusing on further clinical trials to validate its efficacy and safety, as well as exploring its mechanisms of action and potential applications in other cardiovascular conditions.

How should waste containing Omecamtiv mecarbil (CAS: 873697-71-3) be handled?

Waste containing Omecamtiv mecarbil (CAS: 873697-71-3) should be handled by collecting it in appropriate containers and disposing of it through professional waste disposal services. Incineration is a common method, and environmental precautions should be taken to prevent contamination. Compliance with local regulations and guidelines is essential for safe disposal.