2-(3-fluorophenyl)-N-hydroxyethanimidamide | CAS No. 872362-02-2

2-(3-fluorophenyl)-N-hydroxyethanimidamide

Basic Information

CAS Number

872362-02-2

Molecular Formula

C8H9FN2O

Molecular Weight

168.17 g/mol

AD

Basic Physical Properties

C1=CC(=CC(=C1)F)CC(=NO)N

InChI

InChI=1S/C8H9FN2O/c9-7-3-1-2-6(4-7)5-8(10)11-12/h1-4,12H,5H2,(H2,10,11)

InChIKey

MOSPBYILTXWKJK-UHFFFAOYSA-N

LogP

1.32427

Topological Polar Surface Area

56.11 Ų

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

172

Synonyms & References

English

  • (Z)-2-(3-fluorophenyl)-N'-hydroxyethanimidamide
  • 2-(3-fluorophenyl)-N'-hydroxyethanimidamide
  • SCHEMBL100935
  • 2-(3-FLUOROPHENYL)-N-HYDROXYACETIMIDAMIDE
  • AKOS027439770
  • 925252-32-0
  • CS-0208925
  • EN300-1291952
  • MFCD06411153
  • AMY4654
  • DTXSID201247637
  • MFCD07776510
  • BS-3914
  • (1Z)-2-(3-fluorophenyl)-N'-hydroxyethanimidamide
  • [C(Z)]-3-Fluoro-N-hydroxybenzeneethanimidamide
  • AKOS000157396
  • 872362-02-2
  • 2-(3-FLUORO-PHENYL)-N-HYDROXY-ACETAMIDINE
  • 2-(3-fluorophenyl)-N-hydroxyacetimidamide
  • 2-(3-Fluoro-phenyl)-N-hydroxy-acetamidine
  • BENZENEETHANIMIDAMIDE,3-FLUORO-N-HYDROXY-

MDL Number

MFCD09816855

FAQ

What are the physical and chemical properties of 2-(3-fluorophenyl)-N-hydroxyethanimidamide (CAS: 872362-02-2)?

2-(3-fluorophenyl)-N-hydroxyethanimidamide is a crystalline solid with a molecular weight of approximately 223.16 g/mol. It has a low solubility in water but is soluble in organic solvents. The compound exhibits moderate reactivity, particularly towards nucleophiles. It is stable under normal conditions but should be stored away from moisture and heat.

How is 2-(3-fluorophenyl)-N-hydroxyethanimidamide (CAS: 872362-02-2) typically synthesized?

2-(3-fluorophenyl)-N-hydroxyethanimidamide is synthesized through a multi-step process involving the condensation of 3-fluorophenylamine with a suitable carboxylic acid chloride in the presence of a catalytic amount of a base. Common conditions include the use of triethylamine and dichloromethane as the solvent, yielding a high purity product with a good to excellent yield.

What industries use 2-(3-fluorophenyl)-N-hydroxyethanimidamide (CAS: 872362-02-2)?

2-(3-fluorophenyl)-N-hydroxyethanimidamide finds applications in the pharmaceutical industry as a precursor for drug synthesis. It is also utilized in the polymer industry for the development of novel materials with specific properties. Additionally, it has potential uses in the production of sensors and semiconductors due to its chemical reactivity and functional groups.

What precautions should be taken when handling 2-(3-fluorophenyl)-N-hydroxyethanimidamide (CAS: 872362-02-2)?

When handling 2-(3-fluorophenyl)-N-hydroxyethanimidamide, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coat. Work should be conducted in a well-ventilated area or fume hood to minimize inhalation risk. Spills should be cleaned up with caution, using appropriate absorbent materials, and the area should be thoroughly rinsed. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal information.

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