Compound Q&A

How is 2-(3-fluorophenyl)-N-hydroxyethanimidamide (CAS: 872362-02-2) typically synthesized?

Answer

2-(3-fluorophenyl)-N-hydroxyethanimidamide
2-(3-fluorophenyl)-N-hydroxyethanimidamide is synthesized through a multi-step process involving the condensation of 3-fluorophenylamine with a suitable carboxylic acid chloride in the presence of a catalytic amount of a base. Common conditions include the use of triethylamine and dichloromethane as the solvent, yielding a high purity product with a good to excellent yield.

About

English Name 2-(3-fluorophenyl)-N-hydroxyethanimidamide
Molecular Formula C8H9FN2O
Molecular Weight 168.17 g/mol
SMILES C1=CC(=CC(=C1)F)CC(=NO)N
InChIKey MOSPBYILTXWKJK-UHFFFAOYSA-N
Last Updated: 2026-03-10 14:55

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