2,8-Dibromoquinoline

Basic Information

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CAS Number

871507-79-8

Molecular Formula

C9H5Br2N

Molecular Weight

286.95 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

White to Yellow Solid

SMILES

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Brc1ccc2cccc(Br)c2n1

InChI

InChI=1S/C9H5Br2N/c10-7-3-1-2-6-4-5-8(11)12-9(6)7/h1-5H

InChIKey

DPABNLZUYUAAFA-UHFFFAOYSA-N

LogP

3.759800000000001

Topological Polar Surface Area

12.89 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H320 Causes eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

2,8-Dibromoquinoline
2,8-Dibromo-quinoline
2,5-DIMETHYLTHIOPHENE-3-CARBONYL CHLORIDE
AR3599

MDL Number

MFCD09788633

Customs Code

2933499090

FAQ

What are the physical and chemical properties of 2,8-Dibromoquinoline (CAS: 871507-79-8)?

2,8-Dibromoquinoline is a crystalline solid with a molecular weight of approximately 310.05 g/mol. It has a low solubility in water but is soluble in organic solvents such as ethanol and acetone. Chemically, it is moderately reactive, particularly towards nucleophilic substitutions. It is often used as a precursor in organic synthesis due to its bromine substituents.

How is 2,8-Dibromoquinoline (CAS: 871507-79-8) typically synthesized?

2,8-Dibromoquinoline is typically synthesized via a nucleophilic aromatic substitution reaction, where bromine substitutes at the quinoline ring. Common methods include the use of bromine in the presence of a Lewis acid catalyst like aluminum bromide, providing good yield and selectivity. The reaction is exothermic and should be carefully controlled.

What industries use 2,8-Dibromoquinoline (CAS: 871507-79-8)?

2,8-Dibromoquinoline is primarily used in pharmaceuticals for synthesizing key intermediates and in polymer science for developing novel materials with specific properties. It also finds applications in sensor technology and semiconductor industries due to its unique electronic and structural properties.

What precautions should be taken when handling 2,8-Dibromoquinoline (CAS: 871507-79-8)?

When handling 2,8-Dibromoquinoline, it is crucial to wear appropriate personal protective equipment (PPE) including safety goggles, gloves, and a lab coat. Work in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up immediately with appropriate absorbents and waste should be disposed of according to local regulations. Refer to the Safety Data Sheet (SDS) for detailed handling instructions.