3-O-Ethyl-L-Ascorbic Acid

Basic Information

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CAS Number

86404-04-8

Molecular Formula

C8H12O6

Molecular Weight

204.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

Pale-yellow to Yellow-brown Solid

Melting Point

112.0 to 116.0 deg-C

Boiling Point

551.5°C at 760 mmHg

Density

1.46

Flash Point

228.5 °C

Refractive Index

1.555

Specific Rotation

+40 ~ +45° (c=1, MeOH)

SMILES

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O[C@@H](CO)[C@@H](O1)C(OCC)=C(O)C1=O

InChI

InChI=1S/C8H12O6/c1-2-13-7-5(11)8(12)14-6(7)4(10)3-9/h4,6,9-11H,2-3H2,1H3/t4-,6+/m0/s1

InChIKey

ZGSCRDSBTNQPMS-UJURSFKZSA-N

LogP

-0.9288999999999998

Topological Polar Surface Area

96.22 Å²

Hydrogen Bond Donor/Acceptor

3 / 6

Complexity

259

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

3-O-Ethyl-L-ascorbic acid
ETHYL ASCORBIC ACID
(5r)-5-[(1s)-1,2-dihydroxyethyl]-4-ethoxy-3-hydroxy-5h-furan-2-one
3-O-ETHYLASCORBICACID
(5R,1'S)-5-(1,2-Dihydroxy-ethyl)-4-ethoxy-3-hydroxy-5H-furan-2-one
(R)-5-((S)-1,2-dihydroxyethyl)-4-ethoxy-3-hydroxyfuran-2(5H)-one
(5R)-5-(1,2-dihydroxyethyl)-4-ethoxy-3-hydroxy-2,5-dihydrofuran-2-one
(2R)-2-[(1S)-1,2-dihydroxyethyl]-3-ethoxy-4-hydroxy-2H-furan-5-one
3-O-Ethyl Ascorbyl Ether
Vc Ethyl Ether
Vitamin C Ethyl Ether
3-o-ethyl ascorbic acid
3-O-Ethylascorbic acid
L-Ascorbic acid, 3-O-ethyl-
6MW60CB71P
5-(1,2-Dihydroxy-ethyl)-4-ethoxy-3-hydroxy-5H-furan-2-one
(5R)-5-[(1S)-1,2-dihydroxyethyl]-4-ethoxy-3-hydroxyfuran-2(5H)-one
(5R)-5-((1S)-1,2-Dihydroxyethyl)-4-ethoxy-3-hydroxy-5H-furan-2-one
3-O-Ethyl-L-ascorbicacid
A

MDL Number

MFCD09261382

Customs Code

2932209090

FAQ

What is 3-O-Ethyl-L-Ascorbic Acid (CAS: 86404-04-8)?

3-O-Ethyl-L-Ascorbic Acid (CAS: 86404-04-8) is a derivative of ascorbic acid, commonly used as a stable antioxidant. It has the chemical formula C8H12O6 and appears as a white crystalline powder. This compound exhibits strong reducing properties and is soluble in water and ethanol. Its ethyl ester structure enhances solubility and shelf life compared to standard ascorbic acid, making it valuable in various applications. It is often used in formulations requiring prolonged stability and antioxidant activity.

What are the main uses of 3-O-Ethyl-L-Ascorbic Acid (CAS: 86404-04-8)?

3-O-Ethyl-L-Ascorbic Acid (CAS: 86404-04-8) is widely used in pharmaceuticals as a vitamin C derivative for skin health and antioxidant support. In the food industry, it acts as a preservative and stabilizer. It also finds applications in cosmetics for its skin brightening properties and in research for studying antioxidant mechanisms. Its stability under various conditions makes it suitable for industrial processes and product formulation.

Is 3-O-Ethyl-L-Ascorbic Acid (CAS: 86404-04-8) safe?

3-O-Ethyl-L-Ascorbic Acid (CAS: 86404-04-8) is generally considered safe when used as directed. It has low toxicity and is well-tolerated in topical applications. However, ingestion should be avoided unless specified by a professional. Proper handling, such as using gloves and ensuring ventilation, is recommended. Safety standards include compliance with FDA and ICH guidelines for its use in cosmetics and pharmaceuticals.

How should 3-O-Ethyl-L-Ascorbic Acid (CAS: 86404-04-8) be stored?

3-O-Ethyl-L-Ascorbic Acid (CAS: 86404-04-8) should be stored in a cool, dry place, away from light and moisture. Keep it in a sealed, airtight container to maintain stability. It remains chemically stable at temperatures below 25°C and humidity levels under 60%. Avoid exposure to strong oxidizing agents to prevent degradation. Proper storage ensures optimal efficacy and shelf life.