(11beta,16alpha)-11,16,17-Trihydroxy-3,20-dioxopregna-1,4-dien-21-yl acetate | CAS No. 86401-80-1
(11beta,16alpha)-11,16,17-Trihydroxy-3,20-dioxopregna-1,4-dien-21-yl acetate
Basic Information
CAS Number
86401-80-1
Molecular Formula
C23H30O7
Molecular Weight
418.49 g/mol
AD
Chemical Classification
Basic Physical Properties
Boiling Point
593.3°C at 760 mmHg
Density
1.34
Flash Point
202.5°C
Refractive Index
1.629
Synonyms & References
English
- 16alpha-Hydroxyprednisonlone acetate
- 11b,16a,17,21-Tetrahydroxy-pregna-1,4-diene-3,20-dione 21-acetate
- 16a-Hydroxyprednisolone Acetate
- 16A-HYDROOXYPREDNISOLONE ACETATE
- 16α-Hydroxyprednisonlone acetate
- 11b,16a,17 a,21-tetrahydroxylpregn-1,4diene-3,20-dione-21-acetate
- 16A-HYDROXY-PREDNISONLONE ACETATE
- 16alpha-Hydroxy-prednisolone acetate
- 16ALPHA-HYDROXYPRENISOLONEACETATE
- Pregna-1,4-diene-3,20-dione,21-(acetyloxy)-11,16,17-trihydroxy-,(11b,16a)
- [2-Oxo-2-[(8S,9R,10R,11S,13S,14R,16R,17S)-11,16,17-trihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15
- 16α-Hydroxyprednisolone Acetate
- 2-Oxo-2-((8S,9S,10R,11S,13S,14S,16R,17S)-11,16,17-trihydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)ethyl acetate
MDL Number
MFCD08460167
Customs Code
2918199090
FAQ
What are the physical and chemical properties of (11beta,16alpha)-11,16,17-Trihydroxy-3,20-dioxopregna-1,4-dien-21-yl acetate (CAS: 86401-80-1)?
(11beta,16alpha)-11,16,17-Trihydroxy-3,20-dioxopregna-1,4-dien-21-yl acetate is an organic compound with a molecular weight of approximately 426.45 g/mol. It has a crystalline form at room temperature and is poorly soluble in water. The compound exhibits a high reactivity due to the presence of hydroxyl and carbonyl groups, making it susceptible to hydrolysis and oxidation. It is stable under anhydrous and neutral conditions but should be stored under conditions that minimize moisture and oxygen exposure.
How is (11beta,16alpha)-11,16,17-Trihydroxy-3,20-dioxopregna-1,4-dien-21-yl acetate (CAS: 86401-80-1) typically synthesized?
(11beta,16alpha)-11,16,17-Trihydroxy-3,20-dioxopregna-1,4-dien-21-yl acetate is typically synthesized through a multi-step process involving the conversion of progesterone to the target compound. The reaction involves acetylation and subsequent hydroxylation steps, with careful control of reaction conditions to achieve high yields and selectivity. Commonly used catalysts include acid catalysts and enzymes, and the process is optimized for efficiency and environmental friendliness.
What industries use (11beta,16alpha)-11,16,17-Trihydroxy-3,20-dioxopregna-1,4-dien-21-yl acetate (CAS: 86401-80-1)?
(11beta,16alpha)-11,16,17-Trihydroxy-3,20-dioxopregna-1,4-dien-21-yl acetate is primarily used in the pharmaceutical industry for the synthesis of progestogens and other steroid compounds. It is also of interest in research and development for its potential applications in biomedical sensors and semiconductors. Its use in polymer science for the development of novel biomaterials is also under investigation.
What precautions should be taken when handling (11beta,16alpha)-11,16,17-Trihydroxy-3,20-dioxopregna-1,4-dien-21-yl acetate (CAS: 86401-80-1)?
When handling (11beta,16alpha)-11,16,17-Trihydroxy-3,20-dioxopregna-1,4-dien-21-yl acetate, it is essential to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. The compound should be handled in a well-ventilated area or under a fume hood to minimize exposure. Spills should be cleaned up immediately using appropriate absorbents, and the area should be flushed with water. A safety data sheet (SDS) should be consulted for detailed handling and emergency procedures. Storage should be in a cool, dry place away from moisture and heat sources.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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