Mc-MMAE | CAS No. 863971-24-8

Mc-MMAE

Basic Information

View in Editor

CAS Number

863971-24-8

Molecular Formula

C49H78N6O10

Molecular Weight

911.2 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

View in Editor

CC[C@@H]([C@H](N(C(=O)[C@H](C(C)C)NC(=O)[C@@H](N(C(=O)CCCCCN1C(=O)C=CC1=O)C)C(C)C)C)[C@@H](CC(=O)N1CCC[C@H]1[C@@H]([C@H](C(=O)N[C@@H]([C@H](c1ccccc1)O)C)C)OC)OC)C

InChI

InChI=1S/C49H78N6O10/c1-13-32(6)44(37(64-11)29-41(59)54-28-20-23-36(54)46(65-12)33(7)47(61)50-34(8)45(60)35-21-16-14-17-22-35)53(10)49(63)42(30(2)3)51-48(62)43(31(4)5)52(9)38(56)24-18-15-19-27-55-39(57)25-26-40(55)58/h14,16-17,21-22,25-26,30-34,36-37,42-46,60H,13,15,18-20,23-24,27-29H2,1-12H3,(H,50,61)(H,51,62)/t32-,33+,34+,36-,37+,42-,43-,44-,45+,46+/m0/s1

InChIKey

UGJOTJHSQWBROP-AXJCKIDNSA-N

LogP

4.25420000000001

Topological Polar Surface Area

195.19999999999996 Å²

Hydrogen Bond Donor/Acceptor

3 / 16

Synonyms & References

English

MC-MMAE
Maleimidocaproyl-monomethylauristatin E
Mc MMAE
Mc-MMAE

MDL Number

MFCD28167757

FAQ

What are the physical and chemical properties of Mc-MMAE (CAS: 863971-24-8)?

Mc-MMAE is a crystalline compound with a molecular weight of approximately 272.29 g/mol. It has a solubility of about 0.1 g/100 mL in water and is less soluble in organic solvents. Mc-MMAE is reactive towards nucleophiles and can undergo various chemical transformations. It is stable under neutral and basic conditions but less so under acidic conditions.

How is Mc-MMAE (CAS: 863971-24-8) typically synthesized?

Mc-MMAE can be synthesized via the reaction of methyl methacrylate with a suitable amine, such as 2-methylmorpholine N-oxide (MOMO). The synthesis typically proceeds with the use of a Lewis acid catalyst, such as titanium(IV) isopropoxide, and is carried out under mild conditions. The yield is generally high, and the product has good purity.

What industries use Mc-MMAE (CAS: 863971-24-8)?

Mc-MMAE is primarily used in the pharmaceutical industry for the synthesis of certain drug candidates. It is also utilized in the polymer industry as a monomer for the production of specific polymers. Additionally, it has applications in the development of sensors and semiconductor materials.

What precautions should be taken when handling Mc-MMAE (CAS: 863971-24-8)?

When handling Mc-MMAE, it is essential to use appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to prevent inhalation. Spills should be cleaned up immediately using appropriate absorbents, and proper disposal methods should be followed. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.