6-Fluoro-2-quinolinecarboxylic acid

Basic Information

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CAS Number

86324-51-8

Molecular Formula

C10H6FNO2

Molecular Weight

191.16 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

SMILES

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OC(=O)c1ccc2cc(F)ccc2n1

InChI

InChI=1S/C10H6FNO2/c11-7-2-4-8-6(5-7)1-3-9(12-8)10(13)14/h1-5H,(H,13,14)

InChIKey

LNRMNYOWYGXFBK-UHFFFAOYSA-N

LogP

2.0721

Topological Polar Surface Area

50.19 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

234

Synonyms & References

English

6-Fluoroquinoline-2-carboxylic acid
2-Quinolinecarboxylic acid, 6-fluoro-
6-Fluoro-2-quinolinecarboxylic acid
3498AC
6-Fluoro-quinoline-2-carboxylic acid
AB53376
ST24045393
6-fluoroquinoline-2-carboxylic acid

MDL Number

MFCD09837268

FAQ

What are the physical and chemical properties of 6-Fluoro-2-quinolinecarboxylic acid (CAS: 86324-51-8)?

6-Fluoro-2-quinolinecarboxylic acid is a crystalline solid with a molecular weight of approximately 197.13 g/mol. It has a solubility of about 21.4 mg/L in water at 20°C. Chemically, it is reactive towards bases and can undergo substitution reactions. It is also susceptible to hydrolysis in acidic conditions.

How is 6-Fluoro-2-quinolinecarboxylic acid (CAS: 86324-51-8) typically synthesized?

6-Fluoro-2-quinolinecarboxylic acid is usually synthesized by fluorinating 2-quinolinecarboxylic acid. This can be achieved using hydrogen fluoride or other fluorinating agents in the presence of a catalyst. The reaction typically yields a mixture of products, and purification is necessary to obtain the pure compound.

What industries use 6-Fluoro-2-quinolinecarboxylic acid (CAS: 86324-51-8)?

6-Fluoro-2-quinolinecarboxylic acid is used in the pharmaceutical industry for the synthesis of drug intermediates. It also finds applications in the sensor industry due to its unique spectroscopic properties. Additionally, it is used in the polymer industry for modifying properties of certain polymers.

What precautions should be taken when handling 6-Fluoro-2-quinolinecarboxylic acid (CAS: 86324-51-8)?

When handling 6-Fluoro-2-quinolinecarboxylic acid, ensure the use of personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store it in a tightly sealed container and keep it in a cool, dry place away from direct sunlight. In case of spillage, use appropriate spill kits and follow safety data sheet (SDS) guidelines for disposal.