6-Fluoro-2-quinolinecarboxylic acid(CAS: 86324-51-8)

6-Fluoro-2-quinolinecarboxylic acid is a crystalline solid with a molecular weight of approximately 197.13 g/mol. It has a solubility of about 21.4 mg/L in water at 20°C. Chemically, it is reactive towards bases and can undergo substitution reactions. It is also susceptible to hydrolysis in acidic conditions.

6-Fluoro-2-quinolinecarboxylic acid is usually synthesized by fluorinating 2-quinolinecarboxylic acid. This can be achieved using hydrogen fluoride or other fluorinating agents in the presence of a catalyst. The reaction typically yields a mixture of products, and purification is necessary to obtain the pure compound.

6-Fluoro-2-quinolinecarboxylic acid is used in the pharmaceutical industry for the synthesis of drug intermediates. It also finds applications in the sensor industry due to its unique spectroscopic properties. Additionally, it is used in the polymer industry for modifying properties of certain polymers.

When handling 6-Fluoro-2-quinolinecarboxylic acid, ensure the use of personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store it in a tightly sealed container and keep it in a cool, dry place away from direct sunlight. In case of spillage, use appropriate spill kits and follow safety data sheet (SDS) guidelines for disposal.