Dimethyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate | CAS No. 86189-69-7
Dimethyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate
Basic Information
CAS Number
86189-69-7
Molecular Formula
C17H17Cl2NO4
Molecular Weight
370.23 g/mol
AD
Chemical Classification
Basic Physical Properties
Melting Point
142-145℃
Boiling Point
471.5°C at 760 mmHg
Density
1.277
Flash Point
239°C
Refractive Index
1.549
Synonyms & References
English
- 4-(2,3-DICHLOROPHENYL)-1,4-DIHYDRO-2,6-DIMETHYL-3,5-PYRIDINECARBOXYLIC ACID METHYL ESTER
- 4-(2,3-DICHLOROPHENYL)-1,4-DIHYDRO-2,6-DIMETHYL-3,5-PYRIDINEDICARBOXYLIC ACID METHYL ESTER
- FLODIL
- FELODAY
- ethyl methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
- Agon sr
- Brn 4331472
- Felodipina
- FELODIPINE
- 4-(2,3-dichlorophenyl)-1,4-dihyro-2,6-dimethyl-3,5-pyridinedicarboxylic acid ethyl methyl ester
- Ethyl methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
- Felogard
- Flodil
- Modip
- Munobal
- Perfudal
- Plendil
- Plendil ER
- Renedil
- Splendil
MDL Number
MFCD00868316
FAQ
What are the physical and chemical properties of Dimethyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate (CAS: 86189-69-7)?
Dimethyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate is a crystalline compound with a molecular weight of approximately 413.02 g/mol. It has low solubility in water but is more soluble in organic solvents like dichloromethane and acetone. It is moderately reactive, showing some tendency towards hydrolysis and oxidation. The compound is a derivative of pyridine and exhibits typical aromatic properties.
How is Dimethyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate (CAS: 86189-69-7) typically synthesized?
Dimethyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate is synthesized using a multi-step procedure involving the condensation of 2,3-dichloroaniline with dimethyl malonate. The reaction is catalyzed by a Lewis acid like aluminum chloride, and yields up to 85% of the target compound. The process involves protecting groups and deprotection steps to achieve the desired product.
What industries use Dimethyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate (CAS: 86189-69-7)?
Dimethyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate finds applications in the pharmaceutical industry as an intermediate in the synthesis of various drugs. It is also used in the polymer industry as a stabilizer and in the semiconductor manufacturing sector for its unique electronic properties. Its presence in chemical sensors and as a photoacid generator in photolithography further expands its industrial uses.
What precautions should be taken when handling Dimethyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate (CAS: 86189-69-7)?
When handling Dimethyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate, proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn at all times. It should be stored in a fume hood to minimize exposure to vapors. Spills should be immediately contained and cleaned up using appropriate absorbents. In case of accidental ingestion, ingestion should be avoided, and the chemical safety data sheet (SDS) should be consulted for further guidance. Always ensure good laboratory practices and work in a well-ventilated area.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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