S-(Acetamidomethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-cysteine | CAS No. 86060-81-3
S-(Acetamidomethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-cysteine
Basic Information
CAS Number
86060-81-3
Molecular Formula
C21H22N2O5S
Molecular Weight
414.48 g/mol
AD
Basic Physical Properties
Melting Point
147-150 ºC
Density
1.3270
Safety Information
View Safety InformationGHS Hazard Pictograms
H315H319H335Hazard Statement
H315
Causes skin irritation
Skin corrosion/irritation
Skin corrosion/irritation
H319
Causes serious eye irritation
Serious eye damage/eye irritation
Serious eye damage/eye irritation
H335
May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Synonyms & References
English
- Fmoc-S-acetamidomethyl-L-cysteine
- FMOC-L-Cys
- Fmoc-Cys(Acm)-OH
- N-alpha-(9-Fluorenylmethyloxycarbonyl)-S-(acetyl-aminomethyl)-L-cysteine
- N-Fmoc-S-acetamidomethyl-L-cysteine
- (2R)-3-(acetamidomethylsulfanyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
- Fmoc-Cys(Acm)-OH Fmoc-S-acetamidomethyl-L-cysteine
- Nα-Fmoc-S-acetaminomethyl-L-cysteine
MDL Number
MFCD00038769
Customs Code
2930909090
FAQ
What is S-(Acetamidomethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-cysteine (CAS: 86060-81-3)?
S-(Acetamidomethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-cysteine is a derivative of L-cysteine, commonly used in peptide chemistry. It has the CAS number 86060-81-3 and contains a fluorenylmethoxy carbonyl (Fmoc) protecting group. This compound is known for its stability and utility in solid-phase peptide synthesis. Its molecular formula is C19H27N3O5S, and it typically appears as a white to off-white solid with a high melting point.
What are the main uses of S-(Acetamidomethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-cysteine (CAS: 86060-81-3)?
S-(Acetamidomethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-cysteine (CAS: 86060-81-3) is primarily used in the synthesis of peptides and proteins. It serves as a protected amino acid, especially in solid-phase peptide synthesis (SPPS), where the Fmoc group allows for selective deprotection. Additionally, it finds applications in pharmaceutical research, bioconjugation, and as a building block in drug development.
Is S-(Acetamidomethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-cysteine (CAS: 86060-81-3) safe?
S-(Acetamidomethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-cysteine (CAS: 86060-81-3) is generally considered safe when handled properly. However, as a chemical compound, it should be treated with caution, and appropriate safety measures such as gloves and lab ventilation should be used. It is not classified as highly toxic, but its safety data sheet (SDS) should be consulted for detailed handling and exposure guidelines.
How should S-(Acetamidomethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-cysteine (CAS: 86060-81-3) be stored?
S-(Acetamidomethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-cysteine (CAS: 86060-81-3) should be stored in a cool, dry, and dark place, ideally at 2-8°C. It is best kept in a sealed container to prevent moisture and contamination. Avoid exposure to light and ensure it is stored away from incompatible substances to maintain stability and prolong shelf life.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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