Methyl 4-oxo-1,4-dihydro-8-quinolinecarboxylate | CAS No. 860206-84-4

Methyl 4-oxo-1,4-dihydro-8-quinolinecarboxylate

Basic Information

CAS Number

860206-84-4

Molecular Formula

C11H9NO3

Molecular Weight

203.2 g/mol

AD

Basic Physical Properties

COC(=O)C1=CC=CC2=C1NC=CC2=O

InChI

InChI=1S/C11H9NO3/c1-15-11(14)8-4-2-3-7-9(13)5-6-12-10(7)8/h2-6H,1H3,(H,12,13)

InChIKey

VNLGUOZXFZJECD-UHFFFAOYSA-N

LogP

1.3146999999999998

Topological Polar Surface Area

59.160000000000004 Ų

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

311

Synonyms & References

English

  • 4-Oxo-1,4-dihydro-quinoline-8-carboxylic acid methyl ester
  • 860206-84-4
  • 4-Oxo-1,4-dihydroquinoline-8-carboxylic acid methyl ester
  • DTXSID30469484
  • CS-0456505
  • AKOS015901329
  • 4-Hydroxy-quinoline-8-carboxylic acid methyl ester
  • AS-41358
  • Z1509515196
  • SB69752
  • Methyl 4-oxo-1H-quinoline-8-carboxylate
  • Methyl 4-hydroxyquinoline-8-carboxylate
  • SCHEMBL11431252
  • Methyl4-hydroxyquinoline-8-carboxylate
  • methyl 4-oxo-1,4-dihydroquinoline-8-carboxylate
  • A12404
  • EN300-31009711
  • MFCD18417588
  • methyl 4-oxo-1H-quinoline-8-carboxylate
  • methyl 4-hydroxyquinoline-8-carboxylate

MDL Number

MFCD18417588

FAQ

What are the physical and chemical properties of Methyl 4-oxo-1,4-dihydro-8-quinolinecarboxylate (CAS: 860206-84-4)?

Methyl 4-oxo-1,4-dihydro-8-quinolinecarboxylate (CAS: 860206-84-4) is a crystalline solid with a molecular weight of approximately 259.27 g/mol. It is slightly soluble in water and has good solubility in organic solvents like ethanol and methanol. Chemically, it is relatively stable but can react with strong bases. It is not flammable and has a melting point of around 120-125°C.

How is Methyl 4-oxo-1,4-dihydro-8-quinolinecarboxylate (CAS: 860206-84-4) typically synthesized?

Methyl 4-oxo-1,4-dihydro-8-quinolinecarboxylate (CAS: 860206-84-4) is commonly synthesized through the reaction of methyl 8-aminobenzoate with acetic anhydride in the presence of a catalytic amount of acetic acid. This process yields a high degree of selectivity and a good yield of the desired product.

What industries use Methyl 4-oxo-1,4-dihydro-8-quinolinecarboxylate (CAS: 860206-84-4)?

Methyl 4-oxo-1,4-dihydro-8-quinolinecarboxylate (CAS: 860206-84-4) is used in the pharmaceutical industry as an intermediate in the synthesis of various bioactive compounds. It is also utilized in the sensor industry for its potential in detecting specific chemical species.

What precautions should be taken when handling Methyl 4-oxo-1,4-dihydro-8-quinolinecarboxylate (CAS: 860206-84-4)?

Proper handling of Methyl 4-oxo-1,4-dihydro-8-quinolinecarboxylate (CAS: 860206-84-4) includes using personal protective equipment such as gloves and safety goggles. It should be handled in a well-ventilated area or a fume hood. Spills should be cleaned up immediately using appropriate absorbents. Always consult a Safety Data Sheet (SDS) for detailed handling and disposal instructions.

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