2-Chloro-6-(trifluoromethyl)-4-pyrimidinamine

Basic Information

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CAS Number

85730-36-5

Molecular Formula

C5H3ClF3N3

Molecular Weight

197.55 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

191-192 ºC

Boiling Point

316℃ at 760 mmHg

Density

1.598

Flash Point

315.963 °C at 760 mmHg

Refractive Index

1.503

SMILES

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Nc1cc(nc(Cl)n1)C(F)(F)F

InChI

InChI=1S/C5H3ClF3N3/c6-4-11-2(5(7,8)9)1-3(10)12-4/h1H,(H2,10,11,12)

InChIKey

XPOXHSQGNDLFPT-UHFFFAOYSA-N

LogP

1.731

Topological Polar Surface Area

51.8 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

163

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

2-Chloro-6-(trifluoromethyl)pyrimidin-4-amine
2-Chloro-6-(trifluoromethyl)-4-pyrimidinamine
4-Amino-2-chloro-6-trifluoromethylpyrimidine
PubChem17002
SB16104
ST2416765
AB0027040
W8822
4-Amino-2-chloro-6-(trifluoromethyl)pyrimidine
4-Pyrimidinamine,2-chloro-6-(trifluoromethyl)-
730C365
2-chloro-6-(trifluoromethyl)pyrimidin-4-amine

MDL Number

MFCD11558917

Customs Code

2933599090

FAQ

What regulatory guidelines apply to 2-Chloro-6-(trifluoromethyl)-4-pyrimidinamine (CAS: 85730-36-5)?

Regulatory guidelines for 2-Chloro-6-(trifluoromethyl)-4-pyrimidinamine (CAS: 85730-36-5) include GHS classification for hazardous substances, REACH regulations for European manufacturers and importers, and FDA and EPA requirements for its use in the United States. It is classified as a toxic and harmful substance, requiring proper handling and disposal to protect human health and the environment.

Are there alternatives to 2-Chloro-6-(trifluoromethyl)-4-pyrimidinamine (CAS: 85730-36-5) in synthesis?

Alternatives to 2-Chloro-6-(trifluoromethyl)-4-pyrimidinamine (CAS: 85730-36-5) in synthesis include the use of other pyrimidine derivatives, such as 2-amino-6-chloro-4-(trifluoromethyl)pyrimidine, or employing different functional groups in the synthesis pathway. These alternatives can reduce the need for this compound and minimize environmental impact.

What is the market or research trend for 2-Chloro-6-(trifluoromethyl)-4-pyrimidinamine (CAS: 85730-36-5)?

The market for 2-Chloro-6-(trifluoromethyl)-4-pyrimidinamine (CAS: 85730-36-5) is currently stable, with ongoing research focusing on its potential in antiviral and antimicrobial applications. There is a growing trend towards developing safer and more sustainable alternatives, reflecting broader industry shifts towards reducing the use of highly toxic compounds.

How should waste containing 2-Chloro-6-(trifluoromethyl)-4-pyrimidinamine (CAS: 85730-36-5) be handled?

Waste containing 2-Chloro-6-(trifluoromethyl)-4-pyrimidinamine (CAS: 85730-36-5) should be collected in sealed, labeled containers and disposed of through professional waste disposal services. Safe incineration is recommended, with proper environmental precautions to prevent the release of hazardous substances into the environment. Compliance with local and international regulations is essential for safe waste management.