2-(4,6-Dichloro-5-pyrimidinyl)ethanol

Basic Information

View in Editor

CAS Number

853680-74-7

Molecular Formula

C6H6Cl2N2O

Molecular Weight

193.03 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

View in Editor

C1=NC(=C(C(=N1)Cl)CCO)Cl

InChI

InChI=1S/C6H6Cl2N2O/c7-5-4(1-2-11)6(8)10-3-9-5/h3,11H,1-2H2

InChIKey

OTBRMFUGQGCCMO-UHFFFAOYSA-N

LogP

1.3181999999999998

Topological Polar Surface Area

46.010000000000005 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

115

Synonyms & References

English

CS-0266551
FT-0753490
2-(4,6-DICHLOROPYRIMIDIN-5-YL)ETHANOL
SY024461
2-(4,6-Dichloropyrimidin-5-yl)ethan-1-ol
OTBRMFUGQGCCMO-UHFFFAOYSA-N
EN300-201558
A863603
AKOS006336462
DTXSID20681052
SB39045
SCHEMBL783004
AS-31493
2-(4,6-Dichloro-5-pyrimidyl)ethanol
MFCD13181527
2-(4,6-Dichloro-pyrimidin-5-yl)-ethanol
5-Pyrimidineethanol, 4,6-dichloro-
2-(4 pound not6-Dichloro-5-pyrimidyl)ethanol
853680-74-7
2-(4,6-Dichloropyrimidin-5-yl)ethanol
4,6-dichloro- 5-Pyrimidineethanol
2-(2-BROMOPHENYL)-2'-IODOACETOPHENONE
2-(4,6-dichloro-pyrimidin-5-yl)-ethanol
PubChem23143
4,6-dichloro-5-Pyrimidineethanol
5218AJ
FCH923994
TRA0049871
AX8162957

MDL Number

MFCD13181527

Customs Code

2933599090

FAQ

What are the physical and chemical properties of 2-(4,6-Dichloro-5-pyrimidinyl)ethanol (CAS: 853680-74-7)?

2-(4,6-Dichloro-5-pyrimidinyl)ethanol (CAS: 853680-74-7) is a crystalline solid with a molecular weight of approximately 243.02 g/mol. It has a low solubility in water but is soluble in common organic solvents like ethanol and acetone. The compound exhibits moderate reactivity, particularly towards nucleophiles and reducing agents. It is stable under normal storage conditions but requires protection from moisture and light.

How is 2-(4,6-Dichloro-5-pyrimidinyl)ethanol (CAS: 853680-74-7) typically synthesized?

2-(4,6-Dichloro-5-pyrimidinyl)ethanol (CAS: 853680-74-7) can be synthesized through a multi-step process involving the reaction of 2-chloroethanol with 5-chloro-4,6-dichloropyrimidine followed by reduction. Commonly used catalysts include palladium-based catalysts, and the process typically yields a pure product with good selectivity and high yield under controlled conditions.

What industries use 2-(4,6-Dichloro-5-pyrimidinyl)ethanol (CAS: 853680-74-7)?

2-(4,6-Dichloro-5-pyrimidinyl)ethanol (CAS: 853680-74-7) is primarily used in pharmaceuticals for the synthesis of various active pharmaceutical ingredients (APIs). It is also utilized in the polymer industry for the preparation of special polymers, and in the sensor industry for the development of highly sensitive detection devices. Additionally, it finds applications in semiconductor manufacturing processes.

What precautions should be taken when handling 2-(4,6-Dichloro-5-pyrimidinyl)ethanol (CAS: 853680-74-7)?

When handling 2-(4,6-Dichloro-5-pyrimidinyl)ethanol (CAS: 853680-74-7), appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. Storage containers should be tightly sealed and kept in a cool, dry place away from moisture and light. All handling should be conducted in a well-ventilated area or fume hood. In case of spills, neutralize with appropriate chemicals and dispose of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and disposal.