2-(4,6-Dichloro-5-pyrimidinyl)ethanol(CAS: 853680-74-7)

2-(4,6-Dichloro-5-pyrimidinyl)ethanol (CAS: 853680-74-7) is a crystalline solid with a molecular weight of approximately 243.02 g/mol. It has a low solubility in water but is soluble in common organic solvents like ethanol and acetone. The compound exhibits moderate reactivity, particularly towards nucleophiles and reducing agents. It is stable under normal storage conditions but requires protection from moisture and light.

2-(4,6-Dichloro-5-pyrimidinyl)ethanol (CAS: 853680-74-7) can be synthesized through a multi-step process involving the reaction of 2-chloroethanol with 5-chloro-4,6-dichloropyrimidine followed by reduction. Commonly used catalysts include palladium-based catalysts, and the process typically yields a pure product with good selectivity and high yield under controlled conditions.

2-(4,6-Dichloro-5-pyrimidinyl)ethanol (CAS: 853680-74-7) is primarily used in pharmaceuticals for the synthesis of various active pharmaceutical ingredients (APIs). It is also utilized in the polymer industry for the preparation of special polymers, and in the sensor industry for the development of highly sensitive detection devices. Additionally, it finds applications in semiconductor manufacturing processes.

When handling 2-(4,6-Dichloro-5-pyrimidinyl)ethanol (CAS: 853680-74-7), appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. Storage containers should be tightly sealed and kept in a cool, dry place away from moisture and light. All handling should be conducted in a well-ventilated area or fume hood. In case of spills, neutralize with appropriate chemicals and dispose of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and disposal.