4-(Benzyloxy)-2-pyridinamine

Basic Information

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CAS Number

85333-26-2

Molecular Formula

C12H12N2O

Molecular Weight

200.24 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Density

1.180

SMILES

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NC1=NC=CC(OCC2=CC=CC=C2)=C1

InChI

InChI=1S/C12H12N2O/c13-12-8-11(6-7-14-12)15-9-10-4-2-1-3-5-10/h1-8H,9H2,(H2,13,14)

InChIKey

RAFCWIXBEWVPGL-UHFFFAOYSA-N

LogP

2.2428

Topological Polar Surface Area

48.14 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

181

Synonyms & References

English

4-(Benzyloxy)pyridin-2-amine
2-Amino-4-(benzyloxy)pyridine
2-AMINO-4-BENZYLOXYPYRIDINE
4-phenylmethoxypyridin-2-amine
2-Pyridinamine, 4-(phenylmethoxy)-
RAFCWIXBEWVPGL-UHFFFAOYSA-N
4-phenylmethoxy-2-pyridinamine
2-amino-4-phenylmethoxypyridine
4-(Benzyloxy)-2-pyridinamine #
2-Pyridinamine,4-(phenylmethoxy)-
Pyridine, 2-amino-3-(benzyloxy)-
TRA0082925
SY006019
4-(benzyloxy)pyridin-2-amine

MDL Number

MFCD12405835

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 4-(Benzyloxy)-2-pyridinamine (CAS: 85333-26-2)?

4-(Benzyloxy)-2-pyridinamine is a crystalline solid with a molecular weight of approximately 252.25 g/mol. It has a low solubility in water but is more soluble in organic solvents such as methanol and dichloromethane. This compound is relatively stable under normal conditions but can react with strong oxidizing agents. It is often used in the synthesis of other compounds and pharmaceuticals.

How is 4-(Benzyloxy)-2-pyridinamine (CAS: 85333-26-2) typically synthesized?

4-(Benzyloxy)-2-pyridinamine is typically synthesized through a multi-step process involving the coupling of 2-bromopyridine and benzyloxyamine. The synthesis often requires the use of catalysts and reagents like pyridine to enhance reaction selectivity and yield. The final product is isolated by recrystallization or column chromatography.

What industries use 4-(Benzyloxy)-2-pyridinamine (CAS: 85333-26-2)?

4-(Benzyloxy)-2-pyridinamine is primarily used in the pharmaceutical and chemical industries. It serves as a key intermediate in the synthesis of various drugs and other chemical compounds. This compound is also relevant in the development of sensors and materials for semiconductor applications.

What precautions should be taken when handling 4-(Benzyloxy)-2-pyridinamine (CAS: 85333-26-2)?

When handling 4-(Benzyloxy)-2-pyridinamine, it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be stored in a cool, dry place away from oxidizing agents and other reactive materials. Spills should be cleaned up with caution using appropriate absorbents, and proper disposal methods should be followed. Refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.