Ethyl 6-chloro-3-methyl-2-pyridinecarboxylate | CAS No. 850864-54-9
Ethyl 6-chloro-3-methyl-2-pyridinecarboxylate
Basic Information
CAS Number
850864-54-9
Molecular Formula
C9H10ClNO2
Molecular Weight
199.64 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- ethyl 6-chloro-3-Methylpicolinate
- ethyl 6-chloro-3-methylpyridine-2-carboxylate
- ethyl 6-chloro-3-methyl-pyridine-2-carboxylate
MDL Number
MFCD18416525
FAQ
What are the physical and chemical properties of Ethyl 6-chloro-3-methyl-2-pyridinecarboxylate (CAS: 850864-54-9)?
Ethyl 6-chloro-3-methyl-2-pyridinecarboxylate (CAS: 850864-54-9) is a crystalline compound with a molecular weight of approximately 242.68 g/mol. It has low water solubility and is soluble in organic solvents. This compound exhibits moderate reactivity, particularly with nucleophiles. It is stable under normal conditions but should be stored in a cool, dry place away from direct sunlight.
How is Ethyl 6-chloro-3-methyl-2-pyridinecarboxylate (CAS: 850864-54-9) typically synthesized?
Ethyl 6-chloro-3-methyl-2-pyridinecarboxylate (CAS: 850864-54-9) can be synthesized via a Friedel-Crafts acylation reaction, where ethyl acetoacetate is acylated with 3-chloro-6-methylpyridine in the presence of aluminum chloride as a catalyst. This method provides high selectivity and yield, making it a common route for preparation.
What industries use Ethyl 6-chloro-3-methyl-2-pyridinecarboxylate (CAS: 850864-54-9)?
Ethyl 6-chloro-3-methyl-2-pyridinecarboxylate (CAS: 850864-54-9) is utilized in the pharmaceutical industry for the synthesis of certain active pharmaceutical ingredients (APIs). It also has applications in the polymer industry as a monomer for specific polymer synthesis. Additionally, it can be used in the production of sensors and semiconductors.
What precautions should be taken when handling Ethyl 6-chloro-3-methyl-2-pyridinecarboxylate (CAS: 850864-54-9)?
When handling Ethyl 6-chloro-3-methyl-2-pyridinecarboxylate (CAS: 850864-54-9), laboratory personnel should wear appropriate personal protective equipment (PPE), including gloves and safety goggles. It should be stored in a well-ventilated area and handled with care to avoid inhalation or skin contact. In the event of a spill, it is essential to follow proper safety protocols and refer to the Material Safety Data Sheet (MSDS) or Safety Data Sheet (SDS) for detailed instructions.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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