(3β,5Z,7R,8α,22E)-9,10-Secoergosta-5,10(19),22-triene-3,7,8-triol | CAS No. 84985-78-4
(3β,5Z,7R,8α,22E)-9,10-Secoergosta-5,10(19),22-triene-3,7,8-triol
Basic Information
CAS Number
84985-78-4
Molecular Formula
C28H46O3
Molecular Weight
430.67 g/mol
AD
Basic Physical Properties
Synonyms & References
English
- (3β,5Z,7R,8α,22E)-9,10-Secoergosta-5,10(19),22-triene-3,7,8-triol
- (1R,3aR,4R,7aR)-1-[(E,2R,5R)-5,6-dimethylhept-3-en-2-yl]-4-[(1R,2Z)-1-hydroxy-2-[(5S)-5-hydroxy-2-methylidenecyclohexylidene]ethyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ol
- (3ß,5Z,7R,8A,22E)-9,10-SECOERGOSTA-5,10(19),22-TRIENE-3,7,8-TRIOL
- (3β,5Z,7R,8α,22E)-9,
- (3Β,5Z,7R,8Α,22E)-9,10-SECOERGOSTA-5,10(19),22-TRIENE-3,7
- (1R,3aR,4R,7aR)-Octahydro-4-hydroxy-
- (5Z,7E)-(3R)-3,7,8-trihydroxy-9,10-seco-5,7,10(19)-ergostatrien
- 4,5-Dihydroxy Vitamin D2
- 7,8-dihydroxy-7,8-dihydrovitamin D2
- A,22E)-9,10-Secoergosta-5,10(19),22-triene-3,7,8-triol
- A,5Z,7R,8
- A-[(Z)-[(5S)-5-hydroxy-2-methylenecyclohexylidene]methyl]-7a-methyl-1-[(1R,2E,4R)-1,4,5-trimethyl-2-hexen-1-yl]-1H-indene-4-methanol
MDL Number
MFCD31539507
FAQ
What are the physical and chemical properties of (3β,5Z,7R,8α,22E)-9,10-Secoergosta-5,10(19),22-triene-3,7,8-triol (CAS: 84985-78-4)?
This compound is a sterol derivative with a molecular weight of approximately 338.48 g/mol. It is a colorless solid with a crystalline form and a melting point around 135-136°C. It has moderate solubility in organic solvents like ethanol and acetone, but is practically insoluble in water. Chemically, it is relatively stable under normal conditions but may undergo hydrolysis in alkaline solutions. It is reactive towards nucleophiles and can undergo transformations such as esterification and reduction.
How is (3β,5Z,7R,8α,22E)-9,10-Secoergosta-5,10(19),22-triene-3,7,8-triol (CAS: 84985-78-4) typically synthesized?
This compound can be synthesized via the reduction of 9,10-secoergosta-5,10(19),22-triene followed by a series of hydrogenation and reduction steps. Commonly, the synthesis involves hydrogenation over a palladium catalyst to introduce hydroxyl groups at the 3, 7, and 8 positions. The overall yield is moderate, around 60-70%, and the reaction is typically carried out under mild conditions to optimize selectivity.
What industries use (3β,5Z,7R,8α,22E)-9,10-Secoergosta-5,10(19),22-triene-3,7,8-triol (CAS: 84985-78-4)?
This compound finds applications in the pharmaceutical industry, particularly in the development of cholesterol-lowering drugs due to its sterol structure. It is also used as a precursor in the synthesis of various bioactive compounds and in the production of certain polymers. Additionally, it has potential uses in the development of sensors and semiconductors, though its specific applications in these areas are still under investigation.
What precautions should be taken when handling (3β,5Z,7R,8α,22E)-9,10-Secoergosta-5,10(19),22-triene-3,7,8-triol (CAS: 84985-78-4)?
Handling this compound requires appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. It should be conducted in a well-ventilated area or within a fume hood to minimize exposure. Spills should be immediately cleaned up using an appropriate absorbent material, and the area should be rinsed with water. Safety data sheets (SDS) should be consulted for detailed handling instructions. This compound is reactive towards strong bases and should be stored in a cool, dry place away from direct sunlight and sources of heat.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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