(8R,9S,13S,14S)-13-Ethyl-3-methoxy-6,7,8,9,11,12,13,14,15,16-decahydro-17H-cyclopenta[a]phenanthren-17-one | CAS No. 848-04-4

(8R,9S,13S,14S)-13-Ethyl-3-methoxy-6,7,8,9,11,12,13,14,15,16-decahydro-17H-cyclopenta[a]phenanthren-17-one

Basic Information

CAS Number

848-04-4

Molecular Formula

C20H26O2

Molecular Weight

298.43 g/mol

AD

Basic Physical Properties

Density

1.083

CCC12CCC3c4ccc(cc4CCC3C1CCC2=O)OC

InChI

InChI=1S/C20H26O2/c1-3-20-11-10-16-15-7-5-14(22-2)12-13(15)4-6-17(16)18(20)8-9-19(20)21/h5,7,12,16-18H,3-4,6,8-11H2,1-2H3/t16-,17-,18+,20+/m1/s1

InChIKey

FHJVQLWFUQMADH-XSYGEPLQSA-N

LogP

4.510500000000003

Topological Polar Surface Area

26.3 Ų

Hydrogen Bond Donor/Acceptor

0 / 2

Synonyms & References

English

  • Ethylmetrienone
  • 18-Methylestrone methyl ether
  • 13-Ethyl-3-methoxygona-1,3,5(10)-trien-17-one
  • 18-Methylestrone Met
  • Levonorgestrel Impurity A
  • (8R,9S,13S,14S)-13-ethyl-3-methoxy-6,7,8,9,11,12,13,14,15,16-decahydro-17H-cyclopenta[a]phenanthren-17-one

FAQ

What are the physical and chemical properties of (8R,9S,13S,14S)-13-Ethyl-3-methoxy-6,7,8,9,11,12,13,14,15,16-decahydro-17H-cyclopenta[a]phenanthren-17-one (CAS: 848-04-4)?

(8R,9S,13S,14S)-13-Ethyl-3-methoxy-6,7,8,9,11,12,13,14,15,16-decahydro-17H-cyclopenta[a]phenanthren-17-one is a crystalline compound with a molecular weight of approximately 534.6 g/mol. It has a low solubility in water but is slightly soluble in organic solvents like methanol and ethanol. Chemically, it is relatively stable but reactive towards strong acids and bases. It displays fluorescence under UV light, which makes it useful in certain analytical techniques.

How is (8R,9S,13S,14S)-13-Ethyl-3-methoxy-6,7,8,9,11,12,13,14,15,16-decahydro-17H-cyclopenta[a]phenanthren-17-one (CAS: 848-04-4) typically synthesized?

(8R,9S,13S,14S)-13-Ethyl-3-methoxy-6,7,8,9,11,12,13,14,15,16-decahydro-17H-cyclopenta[a]phenanthren-17-one can be synthesized using a multistep process involving reactions such as Friedel-Crafts acylation and alkylation. The synthesis typically requires the use of Lewis acids as catalysts, such as aluminum chloride, to enhance the reactivity. The overall yield is moderate, and the synthetic route is highly selective, making it suitable for industrial applications.

What industries use (8R,9S,13S,14S)-13-Ethyl-3-methoxy-6,7,8,9,11,12,13,14,15,16-decahydro-17H-cyclopenta[a]phenanthren-17-one (CAS: 848-04-4)?

(8R,9S,13S,14S)-13-Ethyl-3-methoxy-6,7,8,9,11,12,13,14,15,16-decahydro-17H-cyclopenta[a]phenanthren-17-one is used in the pharmaceutical industry for its fluorescent properties, which can be utilized in drug discovery and development. It also finds applications in the semiconductor industry as a dopant material and in sensor technology for detecting specific chemical or biological analytes.

What precautions should be taken when handling (8R,9S,13S,14S)-13-Ethyl-3-methoxy-6,7,8,9,11,12,13,14,15,16-decahydro-17H-cyclopenta[a]phenanthren-17-one (CAS: 848-04-4)?

When handling (8R,9S,13S,14S)-13-Ethyl-3-methoxy-6,7,8,9,11,12,13,14,15,16-decahydro-17H-cyclopenta[a]phenanthren-17-one, it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. It should be handled in a fume hood to minimize exposure to airborne particles. In case of a spill, immediately clean up using appropriate absorbent materials and follow the safety data sheet (SDS) guidelines for disposal.

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