Compound Q&A
How is (8R,9S,13S,14S)-13-Ethyl-3-methoxy-6,7,8,9,11,12,13,14,15,16-decahydro-17H-cyclopenta[a]phenanthren-17-one (CAS: 848-04-4) typically synthesized?
Answer
![(8R,9S,13S,14S)-13-Ethyl-3-methoxy-6,7,8,9,11,12,13,14,15,16-decahydro-17H-cyclopenta[a]phenanthren-17-one](https://static.chemtradehub.com/structs/848/848-04-4-adfc.webp "(8R,9S,13S,14S)-13-Ethyl-3-methoxy-6,7,8,9,11,12,13,14,15,16-decahydro-17H-cyclopenta[a]phenanthren-17-one")
(8R,9S,13S,14S)-13-Ethyl-3-methoxy-6,7,8,9,11,12,13,14,15,16-decahydro-17H-cyclopenta[a]phenanthren-17-one can be synthesized using a multistep process involving reactions such as Friedel-Crafts acylation and alkylation. The synthesis typically requires the use of Lewis acids as catalysts, such as aluminum chloride, to enhance the reactivity. The overall yield is moderate, and the synthetic route is highly selective, making it suitable for industrial applications.
About
CAS No
848-04-4
English Name
(8R,9S,13S,14S)-13-Ethyl-3-methoxy-6,7,8,9,11,12,13,14,15,16-decahydro-17H-cyclopenta[a]phenanthren-17-one
Molecular Formula
C20H26O2
Molecular Weight
298.43 g/mol
SMILES
CCC12CCC3c4ccc(cc4CCC3C1CCC2=O)OC
InChIKey
FHJVQLWFUQMADH-XSYGEPLQSA-N
Last Updated: 2026-01-04 19:14
![(8R,9S,13S,14S)-13-Ethyl-3-methoxy-6,7,8,9,11,12,13,14,15,16-decahydro-17H-cyclopenta[a]phenanthren-17-one — Hubei Yangxin Pharmaceutical Technology Co., Ltd.](https://static.chemtradehub.com/suppliers/67cded3957537e5c8069af88/67cded3957537e5c8069af88-logo.webp){kind=logo}