4-Fluoro-2-pyridinecarbonitrile

Basic Information

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CAS Number

847225-56-3

Molecular Formula

C6H3FN2

Molecular Weight

122.1 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Nitriles

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

72-74℃

Boiling Point

221.3 ℃ at 760 mmHg

Density

1.24

Flash Point

88℃

SMILES

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C1=CN=C(C=C1F)C#N

InChI

InChI=1S/C6H3FN2/c7-5-1-2-9-6(3-5)4-8/h1-3H

InChIKey

NIKWVAPXRQHXHR-UHFFFAOYSA-N

LogP

1.09238

Complexity

137

Synonyms & References

English

MFCD09834127
NIKWVAPXRQHXHR-UHFFFAOYSA-N
EN300-123799
CS-0060702
2-Cyano-4-fluoropyridine
847225-56-3
4-fluoropyridine-2-carbonitrile
FT-0646598
AKOS005063484
SCHEMBL1613549
A840899
DTXSID80458606
4-Fluoropicolinonitrile
Y10492
SY035898
AB52749
J-515424
2-Pyridinecarbonitrile, 4-fluoro-
DS-11187
4-fluoro-2-cyano pyridine
2-Pyridinecarbonitrile,4-fluoro
4-fluoranylpyridine-2-carbonitrile
4-fluoro-2-pyridinecarbonitrile

MDL Number

MFCD09834127

FAQ

What are the physical and chemical properties of 4-Fluoro-2-pyridinecarbonitrile (CAS: 847225-56-3)?

4-Fluoro-2-pyridinecarbonitrile is a crystalline compound with a molecular weight of approximately 152.07 g/mol. It is slightly soluble in water but soluble in organic solvents like ethanol and acetonitrile. Chemically, it is reactive and can undergo nucleophilic substitution and coupling reactions.

How is 4-Fluoro-2-pyridinecarbonitrile (CAS: 847225-56-3) typically synthesized?

4-Fluoro-2-pyridinecarbonitrile is typically synthesized by the reaction of 2-cyanopyridine with hydrofluoric acid. The process involves the introduction of a fluorine atom onto the pyridine ring, with high selectivity and moderate yield, making it a common method in the synthesis of fluorinated compounds.

What industries use 4-Fluoro-2-pyridinecarbonitrile (CAS: 847225-56-3)?

4-Fluoro-2-pyridinecarbonitrile is used in various industries, including pharmaceuticals, where it serves as a precursor in the synthesis of drugs. It is also utilized in the production of polymers and sensors due to its functional groups, and in semiconductors for its electronic properties.

What precautions should be taken when handling 4-Fluoro-2-pyridinecarbonitrile (CAS: 847225-56-3)?

Proper handling of 4-Fluoro-2-pyridinecarbonitrile requires the use of personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be stored in a tightly sealed container and handled in a well-ventilated area or fume hood. In case of a spill, it should be cleaned up promptly, and the appropriate safety data sheet (SDS) should be consulted.