4-Fluoro-2-pyridinecarbonitrile(CAS: 847225-56-3)

4-Fluoro-2-pyridinecarbonitrile is a crystalline compound with a molecular weight of approximately 152.07 g/mol. It is slightly soluble in water but soluble in organic solvents like ethanol and acetonitrile. Chemically, it is reactive and can undergo nucleophilic substitution and coupling reactions.

4-Fluoro-2-pyridinecarbonitrile is typically synthesized by the reaction of 2-cyanopyridine with hydrofluoric acid. The process involves the introduction of a fluorine atom onto the pyridine ring, with high selectivity and moderate yield, making it a common method in the synthesis of fluorinated compounds.

4-Fluoro-2-pyridinecarbonitrile is used in various industries, including pharmaceuticals, where it serves as a precursor in the synthesis of drugs. It is also utilized in the production of polymers and sensors due to its functional groups, and in semiconductors for its electronic properties.

Proper handling of 4-Fluoro-2-pyridinecarbonitrile requires the use of personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be stored in a tightly sealed container and handled in a well-ventilated area or fume hood. In case of a spill, it should be cleaned up promptly, and the appropriate safety data sheet (SDS) should be consulted.