4-Hydroxy-2(1H)-pyridinone

Basic Information

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CAS Number

84719-31-3

Molecular Formula

C5H5NO2

Molecular Weight

111.1 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

272-276 °C

Boiling Point

270.9ºC

Density

1.379 g/cm3

Flash Point

117.6ºC

Refractive Index

1.637

SMILES

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Oc1cc[nH]c(=O)c1

InChI

InChI=1S/C5H5NO2/c7-4-1-2-6-5(8)3-4/h1-3H,(H2,6,7,8)

InChIKey

ZEZJPIDPVXJEME-UHFFFAOYSA-N

LogP

0.08049999999999985

Topological Polar Surface Area

53.089999999999996 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

169

Synonyms & References

English

Pyridine-2,4-diol
2,4-Dihydroxypyridine
C5H5NO2
2,4-Pyridinediol
4-Hydroxypyridin-2(1H)-one
4-Hydroxy-2-pyridone
3-Deazauracil
2(1H)-Pyridinone, 4-hydroxy-
2,4-Dihydroxy pyridine
2-hydroxypyridin-4(1H)-one
4-Hydroxy-2(1H)-pyridinone
2(1H)-Pyridinone,4-hydroxy
2(1H)-Pyridone, 4-hydroxy-
NSC37839
4-hydroxy-1,2-dihydropyridin-2-one
4-hydroxy-2(1H)-pyridone
LQ01OR5OK4
ZEZJPIDPVXJEME-UHFFFAOYSA-N

MDL Number

MFCD00006273

FAQ

What are the physical and chemical properties of 4-Hydroxy-2(1H)-pyridinone (CAS: 84719-31-3)?

4-Hydroxy-2(1H)-pyridinone, also known as 4-Hydroxypyridin-2-one, is a crystalline white solid with a molecular weight of approximately 125.12 g/mol. It is slightly soluble in water but more soluble in organic solvents like methanol and ethanol. Chemically, it is a weak acid and can undergo various reactions such as esterification and condensation. It is also known for its reactivity towards nucleophiles and electrophiles.

How is 4-Hydroxy-2(1H)-pyridinone (CAS: 84719-31-3) typically synthesized?

4-Hydroxy-2(1H)-pyridinone can be synthesized through the condensation of 2-hydroxypyridine and acetic anhydride. This reaction is catalyzed by anhydrous hydrogen chloride and typically yields a product with good selectivity and moderate to high yield. Other methods include the oxidation of 2-pyridone with hydrogen peroxide in the presence of a suitable catalyst.

What industries use 4-Hydroxy-2(1H)-pyridinone (CAS: 84719-31-3)?

4-Hydroxy-2(1H)-pyridinone is primarily used in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the polymer industry for the development of novel polymers, in the sensor industry for the fabrication of gas sensors, and in the semiconductor industry for the preparation of organic electronic materials.

What precautions should be taken when handling 4-Hydroxy-2(1H)-pyridinone (CAS: 84719-31-3)?

When handling 4-Hydroxy-2(1H)-pyridinone, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Ensure that the work is conducted in a well-ventilated area or fume hood to minimize inhalation of vapors. Spills should be cleaned up with appropriate absorbents, and the area should be well-ventilated. Always refer to the Material Safety Data Sheet (MSDS) or Safety Data Sheet (SDS) for detailed safety information and emergency procedures.