(1S)-1,5-Anhydro-1-(3-{[5-(4-fluorophenyl)-2-thienyl]methyl}-4-methylphenyl)-D-glucitol | CAS No. 842133-18-0

(1S)-1,5-Anhydro-1-(3-{[5-(4-fluorophenyl)-2-thienyl]methyl}-4-methylphenyl)-D-glucitol

Basic Information

CAS Number

842133-18-0

Molecular Formula

C24H25FO5S

Molecular Weight

444.52 g/mol

AD

Basic Physical Properties

Physical State

Powder

Density

1.364

Cc1ccc(cc1Cc2ccc(s2)c3ccc(cc3)F)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O

InChI

InChI=1S/C24H25FO5S/c1-13-2-3-15(24-23(29)22(28)21(27)19(12-26)30-24)10-16(13)11-18-8-9-20(31-18)14-4-6-17(25)7-5-14/h2-10,19,21-24,26-29H,11-12H2,1H3/t19-,21-,22+,23-,24+/m1/s1

InChIKey

XTNGUQKDFGDXSJ-ZXGKGEBGSA-N

LogP

2.9683200000000047

Topological Polar Surface Area

90.15 Ų

Hydrogen Bond Donor/Acceptor

4 / 5

Synonyms & References

English

  • (1S)-1,5-Anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucitol
  • Canagliflozin
  • TA 7284
  • Canaglifozion
  • Cobicistat
  • D-​Glucitol, 1,​5-​anhydro-​1-​C-​[3-​[[5-​(4-​fluorophenyl)​-​2-​thienyl]​methyl]​-​4-​methylphenyl]​-​, (1S)​-
  • (2S,3R,4R,5S,6R)-2-(3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
  • canagliflozin (*)
  • Canagliflozin purity
  • D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-,(1S)-
  • 1S)-1,5-Anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucitol
  • (2S,3R,4R,5S,6R)-2-(3-((5-(4-Fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

MDL Number

MFCD18251436

FAQ

What is (1S)-1,5-Anhydro-1-(3-{[5-(4-fluorophenyl)-2-thienyl]methyl}-4-methylphenyl)-D-glucitol (CAS: 842133-18-0)?

This compound is a derivative of D-glucitol, characterized by its complex structure featuring a 4-fluorophenyl group and a thienyl ring. It is a white solid with high molecular weight and is known for its stability under normal conditions. The compound is primarily used in specialized chemical research and pharmaceutical development due to its functional groups and potential biological activity.

What are the main uses of (1S)-1,5-Anhydro-1-(3-{[5-(4-fluorophenyl)-2-thienyl]methyl}-4-methylphenyl)-D-glucitol (CAS: 842133-18-0)?

This compound is mainly used in the pharmaceutical industry for the development of drugs targeting specific biological pathways. It also finds application in chemical research for the synthesis of more complex molecules and in the study of carbohydrate derivatives. Its utility is further extended to industrial processes that require precise chemical intermediates.

Is (1S)-1,5-Anhydro-1-(3-{[5-(4-fluorophenyl)-2-thienyl]methyl}-4-methylphenyl)-D-glucitol (CAS: 842133-18-0) safe?

As a research chemical, this compound is generally considered safe when handled according to standard laboratory protocols. However, it should be treated with care, as it may have potential irritant properties. Safety data sheets (SDS) recommend using appropriate protective equipment and following good chemical hygiene practices to minimize exposure and ensure safe handling.

How should (1S)-1,5-Anhydro-1-(3-{[5-(4-fluorophenyl)-2-thienyl]methyl}-4-methylphenyl)-D-glucitol (CAS: 842133-18-0) be stored?

This compound should be stored in a cool, dry, and dark place, ideally at 2-8°C. It is best kept in airtight, moisture-proof containers to prevent degradation. Avoid exposure to direct sunlight and ensure it is stored away from incompatible substances to maintain its stability and integrity over time.

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