2-Chloro-5-fluorobenzaldehyde

Basic Information

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CAS Number

84194-30-9

Molecular Formula

C7H4ClFO

Molecular Weight

158.56 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Aldehydes

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

47.0 to 51.0 deg-C

Boiling Point

207.2℃ at 760 mmHg

Density

1.352

Flash Point

80.9℃

Refractive Index

1.559

SMILES

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Fc1ccc(Cl)c(C=O)c1

InChI

InChI=1S/C7H4ClFO/c8-7-2-1-6(9)3-5(7)4-10/h1-4H

InChIKey

SOEFVBXUNROUOX-UHFFFAOYSA-N

LogP

2.2916000000000007

Topological Polar Surface Area

17.07 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

129

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

2-Chloro-5-fluorobenzaldehyde
5-FLUORO-2-CHLOROBENZALDEHYDE
Benzaldehyde,2-chloro-5-fluoro
Benzaldehyde, 2-chloro-5-fluoro-
2-Chloro-5-Fluoro benzaldehyde
2-chloro-5-fluoro-benzaldehyde
PubChem1410
KSC494E5R
4-Fluoro-3-nitrobenzofluoride
SOEFVBXUNROUOX-UHFFFAOYSA-N
EBD23195
SBB063392
TRA0021223
LF10679
AS01060
CM11877
AM62114
AS01438
K503
AK-2
2-chloro-5-fluorobenzaldehyde

MDL Number

MFCD03788511

FAQ

What are the physical and chemical properties of 2-Chloro-5-fluorobenzaldehyde (CAS: 84194-30-9)?

2-Chloro-5-fluorobenzaldehyde (CAS: 84194-30-9) is a crystalline solid with a molecular weight of approximately 168.01 g/mol. It has a moderate solubility in water (0.12 g/100 mL at 25°C) and is highly soluble in organic solvents such as ethanol and acetone. The compound is moderately reactive, showing good stability towards heat and light. It can undergo electrophilic aromatic substitution and addition reactions under appropriate conditions.

How is 2-Chloro-5-fluorobenzaldehyde (CAS: 84194-30-9) typically synthesized?

2-Chloro-5-fluorobenzaldehyde (CAS: 84194-30-9) can be synthesized by the reaction of 5-fluorobenzaldehyde with chlorine gas in the presence of a Lewis acid catalyst such as aluminum chloride. The yield is typically around 70-80%, and the reaction is highly selective for the chlorination position. Other methods include direct chlorination of 5-fluorobenzene in an acidic medium.

What industries use 2-Chloro-5-fluorobenzaldehyde (CAS: 84194-30-9)?

2-Chloro-5-fluorobenzaldehyde (CAS: 84194-30-9) is primarily used in the pharmaceutical industry, where it serves as a precursor for the synthesis of various drugs. It is also utilized in the preparation of dyes, polymers, and electronic materials. Additionally, it finds applications in the development of sensors and semiconductor devices due to its unique chemical properties.

What precautions should be taken when handling 2-Chloro-5-fluorobenzaldehyde (CAS: 84194-30-9)?

When handling 2-Chloro-5-fluorobenzaldehyde (CAS: 84194-30-9), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight and sources of ignition. Proper ventilation is required during handling to avoid inhalation of vapors. In case of spill, do not touch the spilled material, and follow the material safety data sheet (MSDS/SDS) guidelines for cleanup. Always consult the SDS for specific safety information.