2-Chloro-5-fluorobenzaldehyde(CAS: 84194-30-9)

2-Chloro-5-fluorobenzaldehyde (CAS: 84194-30-9) is a crystalline solid with a molecular weight of approximately 168.01 g/mol. It has a moderate solubility in water (0.12 g/100 mL at 25°C) and is highly soluble in organic solvents such as ethanol and acetone. The compound is moderately reactive, showing good stability towards heat and light. It can undergo electrophilic aromatic substitution and addition reactions under appropriate conditions.

2-Chloro-5-fluorobenzaldehyde (CAS: 84194-30-9) can be synthesized by the reaction of 5-fluorobenzaldehyde with chlorine gas in the presence of a Lewis acid catalyst such as aluminum chloride. The yield is typically around 70-80%, and the reaction is highly selective for the chlorination position. Other methods include direct chlorination of 5-fluorobenzene in an acidic medium.

2-Chloro-5-fluorobenzaldehyde (CAS: 84194-30-9) is primarily used in the pharmaceutical industry, where it serves as a precursor for the synthesis of various drugs. It is also utilized in the preparation of dyes, polymers, and electronic materials. Additionally, it finds applications in the development of sensors and semiconductor devices due to its unique chemical properties.

When handling 2-Chloro-5-fluorobenzaldehyde (CAS: 84194-30-9), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight and sources of ignition. Proper ventilation is required during handling to avoid inhalation of vapors. In case of spill, do not touch the spilled material, and follow the material safety data sheet (MSDS/SDS) guidelines for cleanup. Always consult the SDS for specific safety information.