(2S)-3-(4-Cyanophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide | CAS No. 841205-47-8

(2S)-3-(4-Cyanophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide

Basic Information

CAS Number

841205-47-8

Molecular Formula

C19H14F3N3O3

Molecular Weight

389.33 g/mol

AD

Basic Physical Properties

Melting Point

70–74 °C (158–165 °F)

Boiling Point

632.261 °C at 760 mmHg

Density

1.418

Flash Point

336.18 °C

C[C@](COc1ccc(cc1)C#N)(C(=O)Nc2ccc(c(c2)C(F)(F)F)C#N)O

InChI

InChI=1S/C19H14F3N3O3/c1-18(27,11-28-15-6-2-12(9-23)3-7-15)17(26)25-14-5-4-13(10-24)16(8-14)19(20,21)22/h2-8,27H,11H2,1H3,(H,25,26)/t18-/m0/s1

InChIKey

JNGVJMBLXIUVRD-SFHVURJKSA-N

Complexity

658

Synonyms & References

English

  • (S)-N-(4-cyano-3-(trifluoromethyl)phenyl)-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide
  • Ostarine
  • (S)-3-(4-Cyanophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropionamide
  • MK-2866
  • MK-2866 (GTx-024)
  • MK-2866 (Ostarine)
  • Ostarine NOT FOR SAL
  • Ostarine NOT FOR SALE-PATENTED
  • OSTARINE(MK-2866)
  • MK2866
  • Enobosarm
  • Enobosarmum

MDL Number

MFCD16877675

FAQ

What are the physical and chemical properties of (2S)-3-(4-Cyanophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide (CAS: 841205-47-8)?

The compound (2S)-3-(4-Cyanophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide has a crystalline form with a molecular weight of approximately 491.34 g/mol. It is slightly soluble in water but highly soluble in organic solvents like DMSO and acetonitrile. The compound exhibits significant reactivity towards nucleophiles and is less reactive towards electrophiles. It is stable under normal conditions but may degrade under strong acidic or basic conditions.

How is (2S)-3-(4-Cyanophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide (CAS: 841205-47-8) typically synthesized?

This compound is typically synthesized by a multi-step process involving the coupling of 4-cyanophenol with 4-cyano-3-(trifluoromethyl)benzaldehyde followed by the formation of the amide via a condensation reaction. The synthesis involves the use of a Lewis acid catalyst and proceeds with good selectivity and yield. The exact method and conditions can vary, but the overall process is known to be efficient and reproducible.

What industries use (2S)-3-(4-Cyanophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide (CAS: 841205-47-8)?

This compound is primarily used in the pharmaceutical industry for the development of novel drugs. It also finds applications in the production of functional polymers, sensors, and semiconductors due to its unique chemical properties. The compound's ability to interact with specific molecules makes it valuable in various advanced materials and technologies.

What precautions should be taken when handling (2S)-3-(4-Cyanophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide (CAS: 841205-47-8)?

When handling this compound, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or within a fume hood to minimize exposure. Spills should be handled carefully using appropriate absorbents, and the material safety data sheet (MSDS) should be consulted for specific guidelines. This compound should be stored in a cool, dry place away from direct sunlight and heat sources to maintain its stability.

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