Compound Q&A
How is (2S)-3-(4-Cyanophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide (CAS: 841205-47-8) typically synthesized?
Answer
![(2S)-3-(4-Cyanophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide](https://static.chemtradehub.com/structs/841/841205-47-8-fa6a.webp "(2S)-3-(4-Cyanophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide")
This compound is typically synthesized by a multi-step process involving the coupling of 4-cyanophenol with 4-cyano-3-(trifluoromethyl)benzaldehyde followed by the formation of the amide via a condensation reaction. The synthesis involves the use of a Lewis acid catalyst and proceeds with good selectivity and yield. The exact method and conditions can vary, but the overall process is known to be efficient and reproducible.
About
CAS No
841205-47-8
English Name
(2S)-3-(4-Cyanophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide
Molecular Formula
C19H14F3N3O3
Molecular Weight
389.32796 g/mol
SMILES
C[C@](COc1ccc(cc1)C#N)(C(=O)Nc2ccc(c(c2)C(F)(F)F)C#N)O
InChIKey
JNGVJMBLXIUVRD-SFHVURJKSA-N
Last Updated: 2025-09-22 19:21
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